1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine

Basic Information

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CAS Number

70627-52-0

Molecular Formula

C20H16FNO

Molecular Weight

305.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

134.0 to 138.0 deg-C

Boiling Point

455.2℃/760mmHg

Density

1.07

SMILES

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C1=CC=C(C=C1)COC2=CC=C(C=C2)C=NC3=CC=C(C=C3)F

InChI

InChI=1S/C20H16FNO/c21-18-8-10-19(11-9-18)22-14-16-6-12-20(13-7-16)23-15-17-4-2-1-3-5-17/h1-14H,15H2

InChIKey

IWNBEFDVKWCBFY-UHFFFAOYSA-N

LogP

5.155300000000004

Topological Polar Surface Area

21.59 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

351

Synonyms & References

English

4-BENZYLOXYBENZYLIDENE 4-FLUOROANILINE
70627-52-0
AMY4171
SY055798
A836946
DS-3355
8T6S6LX5B3
4-Benzyloxybenzylidene-(4-fluoro)aniline
(Z)-1-[4-(benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine
CS-0156173
N-(4-fluorophenyl)-4-benzyloxybenzylideneamine
Benzenamine, 4-fluoro-N-[[4-(phenylmethoxy)phenyl]methylene]
4, 4-Benzyloxybenzylidene P- Fluoroaniline
(Z)-1-(4-(Benzyloxy)phenyl)-N-(4-fluorophenyl)methanimine
E-N-(4-(BENZYLOXY)BENZYLIDENE)-4-FLUOROANILINE
Benzenamine, 4-fluoro-N-[[4-(phenylmethoxy)phenyl]methylene]-
BENZENAMINE, 4-FLUORO-N-((4-(PHENYLMETHOXY)PHENYL)METHYLENE)-
DTXSID30355111
AKOS028109091
starbld0004881
FT-0641305
AC-8739
BCP04589
4 inverted exclamation mark -(Benzyloxy)benzylidene-4-fluoroaniline
AC7919
n-(4-benzyloxybenzylidene)-4-fluoroaniline
AKOS025401250
219653-96-0
(E)-N-(4-(benzyloxy)benzylidene)-4-fluoroaniline
IWNBEFDVKWCBFY-HYARGMPZSA-N
C20H16FNO

MDL Number

MFCD00017951

FAQ

What are the physical and chemical properties of 1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0)?

1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0) is a white to off-white solid crystalline compound with a molecular weight of approximately 366.34 g/mol. It has limited water solubility and good solubility in organic solvents such as dichloromethane and acetone. The compound is prone to hydrolysis and is not very reactive under normal conditions. It is stable in an inert atmosphere, but care should be taken to avoid moisture exposure.

How is 1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0) typically synthesized?

1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0) is typically synthesized via a multi-step process involving the coupling of 4-(benzyloxy)aniline and 4-fluorobenzoyl chloride. The reaction is catalyzed by a suitable acid or a phase-transfer catalyst, and the process yields a high purity product with good selectivity. The reaction is carried out under anhydrous conditions to prevent side reactions.

What industries use 1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0)?

1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0) is primarily used in the pharmaceutical and fine chemical industries for the synthesis of lead compounds and intermediates. It also has applications in the polymer industry as a precursor for various functional polymers and in the semiconductor industry as a dopant material for organic semiconductors.

What precautions should be taken when handling 1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0)?

When handling 1-[4-(Benzyloxy)phenyl]-N-(4-fluorophenyl)methanimine (CAS: 70627-52-0), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. The compound should be stored in a cool, dry, and well-ventilated area, away from moisture and heat sources. In case of spill, it should be handled using appropriate spill kits, and the material safety data sheet (MSDS) should be consulted for specific handling instructions.