4-Chloro-1H-benzimidazol-2-amine

Basic Information

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CAS Number

701-14-4

Molecular Formula

C7H6ClN3

Molecular Weight

167.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

180-190 °C

Density

1.533±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC2=C(C(=C1)Cl)N=C(N2)N

InChI

InChI=1S/C7H6ClN3/c8-4-2-1-3-5-6(4)11-7(9)10-5/h1-3H,(H3,9,10,11)

InChIKey

WDGDTHWKGHBYNL-UHFFFAOYSA-N

LogP

1.7984999999999998

Topological Polar Surface Area

54.699999999999996 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

153

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-Chloro-1H-benzo[d]imidazol-2-amine
DS-3602
AKOS011972914
O11197
4-Chloro-1H-benzimidazol-2-amine
701-14-4
4-chloro-1H-1,3-benzodiazol-2-amine
SCHEMBL215756
SY043147
EN300-104576
DTXSID60597421
CS-W004430
7-chloro-1h-benzo[d]imidazol-2-amine
7-CHLORO-1H-BENZOIMIDAZOL-2-YLAMINE
2-Amino-7-chloro-1H-benzimidazole, 95%
SB38385
2-amino-7-chlorobenzimidazole
WDGDTHWKGHBYNL-UHFFFAOYSA-N
MFCD21640578
1H-Benzimidazol-2-Amine,4-Chloro-(9CI)
AKOS016001569
7-chloro-1H-Benzimidazol-2-amine
4-CHLORO-1H-BENZO[D]IMIDAZOL-2-AMINE
4-chloro-2-aminobenzimidazole
2-amino-4-chloro-benzimidazole
4-Chlor-2-amino-benzimidazol
4-chloro-1(3)H-benzoimidazol-2-ylamine
4-chloro-1H-benzo[d]imidazol-2-ylamine
ANW-69987
CTK8C3351
SureCN215756

MDL Number

MFCD16652304

FAQ

What regulatory guidelines apply to 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4)?

4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4) falls under the scope of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which mandates hazard communication including safety data sheets and proper labeling. It is also subject to the European Union's Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation, which includes registration, risk assessment, and authorization procedures. Additionally, it may be regulated by the U.S. Food and Drug Administration (FDA) for pharmaceutical uses and the Environmental Protection Agency (EPA) for environmental and safety concerns.

Are there alternatives to 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4) in synthesis?

Yes, there are several alternatives to 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4) in synthesis, such as other benzimidazole derivatives like 1-H-benzimidazol-2-amine, or related compounds like 4-methyl-1H-benzimidazol-2-amine. These alternatives can offer similar or different functional groups for various applications, depending on the specific requirements of the synthesis process.

What is the market or research trend for 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4)?

The market for 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4) is currently stable, with ongoing research focusing on its potential uses in pharmaceuticals, agricultural chemicals, and materials science. Recent trends indicate an increasing interest in developing novel derivatives and analogs with improved properties, such as enhanced stability, bioavailability, or specific biological activities.

How should waste containing 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4) be handled?

Waste containing 4-Chloro-1H-benzimidazol-2-amine (CAS: 701-14-4) should be collected and disposed of according to local regulations and safety guidelines. It is recommended to neutralize the waste to reduce the risk of environmental contamination and then incinerate it in a controlled environment or use a professional waste disposal service. Proper handling and disposal methods should be documented and followed to ensure compliance with regulatory requirements and environmental protection.