Ormetoprim Standard

Basic Information

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CAS Number

6981-18-6

Molecular Formula

C14H18N4O2

Molecular Weight

274.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

231.0 to 235.0 deg-C

Boiling Point

521.5±60.0 °C at 760 mmHg

Density

1.1000

Flash Point

269.2±32.9 °C

Refractive Index

1.609

SMILES

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COc1cc(Cc2cnc(nc2N)N)c(cc1OC)C

InChI

InChI=1S/C14H18N4O2/c1-8-4-11(19-2)12(20-3)6-9(8)5-10-7-17-14(16)18-13(10)15/h4,6-7H,5H2,1-3H3,(H4,15,16,17,18)

InChIKey

KEEYRKYKLYARHO-UHFFFAOYSA-N

LogP

1.55742

Topological Polar Surface Area

96.28 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

305

Synonyms & References

English

ormetoprim
5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine
Ormetoprim Solution
component of Rofenaid
Ormethoprim
Ormetorprim
Ro 5-9754
2,4-Diamino-5-(4,5-dimethoxy-2-methylbenzyl)pyrimidine
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
2,4-Diamino-5-(6-methylveratryl)pyrimidine
M3EFS94984
2,4-Pyrimidinediamine, 5-[(4,5-dimethoxy-2-methylphenyl)methyl]-
NSC95072
DSSTox_RID_81823
DSSTox_CID_26689
DSSTox_GSID_46689
Ormetoprima
Ormetop
Ormetoprim Standard

MDL Number

MFCD00057747

FAQ

What are the physical and chemical properties of Ormetoprim Standard (CAS: 6981-18-6)?

Ormetoprim Standard (CAS: 6981-18-6) is a white crystalline solid with a molecular weight of approximately 313.7 g/mol. It is poorly soluble in water but readily dissolves in common organic solvents like methanol and ethanol. Chemically, it is relatively stable but can degrade under strong acidic or alkaline conditions. It has a low reactivity towards common reagents and is generally considered safe under normal handling conditions.

How is Ormetoprim Standard (CAS: 6981-18-6) typically synthesized?

Ormetoprim Standard (CAS: 6981-18-6) is synthesized through a multi-step process involving the reaction of a substituted pyrimidine with a substituted amino acid derivative. The synthesis typically involves basic conditions and the use of an appropriate solvent. The process has a good overall yield and moderate to high selectivity, with common catalysts including triethylamine and potassium carbonate.

What industries use Ormetoprim Standard (CAS: 6981-18-6)?

Ormetoprim Standard (CAS: 6981-18-6) is primarily used in the veterinary pharmaceutical industry as an antibacterial agent. It is also explored for its potential in agricultural applications to control bacterial infections in livestock. Additionally, it is of interest in research for its antimicrobial properties and may find applications in the development of new antimicrobial agents.

What precautions should be taken when handling Ormetoprim Standard (CAS: 6981-18-6)?

When handling Ormetoprim Standard (CAS: 6981-18-6), it is important to use personal protective equipment (PPE) such as gloves and safety goggles to protect against skin contact and eye exposure. It should be stored in a cool, dry place away from direct sunlight. In the case of a spill, it should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.