5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione

Basic Information

View in Editor

CAS Number

69408-81-7

Molecular Formula

C16H17N3O2

Molecular Weight

283.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

162-164°C

Boiling Point

500.2°C at 760 mmHg

SMILES

View in Editor

CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)N

InChI

InChI=1S/C16H17N3O2/c1-18(2)6-7-19-15(20)12-5-3-4-10-8-11(17)9-13(14(10)12)16(19)21/h3-5,8-9H,6-7,17H2,1-2H3

InChIKey

UPALIKSFLSVKIS-UHFFFAOYSA-N

LogP

1.5796

Topological Polar Surface Area

66.64 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

437

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

SMR000528907
1H-Benz[de]isoquinoline-1, 5-amino-2-[2-(dimethylamino)ethyl]-
Amonafide [USAN:INN]
BRD-K56334280-001-02-8
CHEBI:94661
UNII-1Q8D39N37L
NSC-308847
BCP9000321
Amonafida
AS1413
AC-22581
NSC308847
3-Amino-N-(2-(dimethylamino)ethyl)-1,8-naphthalindicarboximid
CS-0496
1H-Benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(dimethylamino)ethyl-
Amonafide (USAN)
DTXSID30219562
NSC 308847
A24926
5-Amino-2-(2-dimethylamino-ethyl)-benzo[de]isoquinoline-1,3-dione (amonafide)
Amonafide [INN]
CHEMBL428676
AMONAFIDE [WHO-DD]
NSC-758251
Amonafida [Spanish]
HY-10982
AS-1413(Amonafide)
MLS000757039
NSC758251
5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione;Amonafide.
SW219946-1

MDL Number

MFCD00866438

FAQ

What regulatory guidelines apply to 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS: 69408-81-7)?

Regulatory guidelines for 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS: 69408-81-7) include GHS classification, REACH regulations, and FDA and EPA requirements. It is classified as a hazardous substance due to its potential for skin and eye irritation, and may require specific handling and storage procedures. Compliance with local and national regulations is essential for its safe use and disposal.

Are there alternatives to 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione in synthesis (CAS: 69408-81-7)?

Yes, there are alternatives to 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione in synthesis. Common alternatives include other isoquinoline derivatives and related compounds such as 1-(2-dimethylaminoethyl)-3-aminobenzene. These alternatives can offer similar functionalities but with varying reactivity and toxicity profiles, providing flexibility in synthetic strategies.

What is the market or research trend for 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS: 69408-81-7)?

Market and research trends for 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS: 69408-81-7) are focused on its potential applications in pharmaceuticals and agrochemicals. Ongoing research explores its biological activity, such as its use as a potential antiparasitic agent. Market demand is driven by increasing emphasis on novel compounds for treating parasitic diseases and enhancing crop yield.

How should waste containing 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS: 69408-81-7) be handled?

Waste containing 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS: 69408-81-7) should be handled according to local waste management regulations. Waste liquids should be collected in appropriate containers, labeled with the correct hazard warnings, and stored in a secure location. Incineration or professional waste disposal services are recommended. Ensure all handling procedures comply with environmental protection measures to prevent contamination of the environment.