(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride

Basic Information

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CAS Number

6780-38-7

Molecular Formula

C10H6ClNO3

Molecular Weight

223.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

343.2 °C at 760 mmHg

Density

1.504

Flash Point

343.2 °C at 760 mmHg

Refractive Index

1.614

SMILES

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C1=CC=C2C(=C1)C(=O)N(C2=O)CC(=O)Cl

InChI

InChI=1S/C10H6ClNO3/c11-8(13)5-12-9(14)6-3-1-2-4-7(6)10(12)15/h1-4H,5H2

InChIKey

RHZBRCQIKQUQHQ-UHFFFAOYSA-N

LogP

1.048

Topological Polar Surface Area

54.45 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

305

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

N-PHTHALYLGLYCYL CHLORIDE
2H-Isoindole-2-acetyl chloride, 1,3-dihydro-1,3-dioxo-
(1,3-Dioxo-1,3-dihydroisoindol-2-yl)acetyl chloride
2-Isoindolineacetyl chloride, 1,3-dioxo-
Phthalylglycyl chloride
5-21-10-00440 (Beilstein Handbook Reference)
F2146-0396
phthalimidoacetic acid chloride
W-104702
2-(1,3-dioxoisoindol-2-yl)acetyl chloride
(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-acetyl chloride
Phthalimidoacetyl chloride
SCHEMBL252198
NSC-401729
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetyl chloride
SY083619
2-(1,3-Dioxoisoindolin-2-yl)acetylchloride
Phthalylglycine acid chloride
Phthalylglycyl chloride, 96%
SB66149
EN300-114697
MFCD00192872
2-(1,3-Dioxoisoindolin-2-yl)acetyl chloride
AKOS005141601
(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride
FT-0649161
A835888
2-phthalimidoacetyl chloride
2H-Isoindole-2-acetyl chloride,3-dihydro-1,3-dioxo-
NSC 401729
EINECS 229-840-8

MDL Number

MFCD00192872

Customs Code

2925190090

FAQ

What is (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride (CAS: 6780-38-7)?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride is a chemical compound with the CAS number 6780-38-7. It is a white crystalline solid with a pungent odor, used primarily in organic synthesis and pharmaceuticals. This compound is known for its reactivity and can be used as an acylating agent.

What are the main uses of (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride (CAS: 6780-38-7)?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride is mainly used in the synthesis of pharmaceuticals, specifically in the production of drugs and intermediates. It is also used in organic chemistry as a reagent for acylation reactions.

Is (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride (CAS: 6780-38-7) safe?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride can be handled with appropriate safety measures. It is important to use personal protective equipment (PPE) such as gloves and goggles. Avoid contact with skin and eyes, and handle in a well-ventilated area to minimize inhalation. Proper storage and disposal procedures should be followed to ensure safety.

How should (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride (CAS: 6780-38-7) be stored?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride should be stored in a cool, dry place away from direct sunlight and heat sources. Keep it in a tightly sealed container to prevent moisture and light exposure. It should be stored at a temperature below 25°C (77°F) to ensure stability and safety.