2,4-Diphenyl-1H-imidazole

Basic Information

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CAS Number

670-83-7

Molecular Formula

C15H12N2

Molecular Weight

220.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

461.2°C at 760 mmHg

SMILES

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C1=CC=C(C=C1)C2=CN=C(N2)C3=CC=CC=C3

InChI

InChI=1S/C15H12N2/c1-3-7-12(8-4-1)14-11-16-15(17-14)13-9-5-2-6-10-13/h1-11H,(H,16,17)

InChIKey

FHHCKYIBYRNHOZ-UHFFFAOYSA-N

LogP

3.7437000000000014

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

229

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

67-08-3
1H-Imidazole,4-diphenyl-
NSC167196
2,5-Diphenylimidazole
2,4-Diphenylimidazole
2,4-Diphenyl-1H-imidazole #
SCHEMBL16900284
AKOS015904049
A9007
2,4-Diphenyl-1H-imidazole
PD189091
2,4-Diphenylimidazol
MFCD07772899
670-83-7
CHEMBL327027
BDBM50133778
FT-0659011
1H-Imidazole, 2,4-diphenyl-
SY041700
SCHEMBL528246
CS-0156399
AC-1516
Imidazole, 2,4-diphenyl-
Imidazole, 2,4(or 2,5)-diphenyl-
2,4-diphenyl-1H-imidazole;2,5-Diphenyl-1H-imidazole
2,4-diphenyl imidazole
2,4(5)-Diphenylimidazole
AKOS025117309
TS-00502
AM85870
NSC-167196

MDL Number

MFCD07782111

FAQ

What are the physical and chemical properties of 2,4-Diphenyl-1H-imidazole (CAS: 670-83-7)?

2,4-Diphenyl-1H-imidazole (CAS: 670-83-7) is a crystalline solid with a molecular weight of approximately 244.25 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and ethanol. Chemically, it demonstrates limited reactivity under normal conditions, making it stable in air and moisture. Its physical properties include a melting point of around 170-172°C.

How is 2,4-Diphenyl-1H-imidazole (CAS: 670-83-7) typically synthesized?

2,4-Diphenyl-1H-imidazole (CAS: 670-83-7) is typically synthesized through multistep reactions involving phenylacetylene and phenylhydrazine. The synthesis involves the condensation of these reagents under conditions of mild heat, often in the presence of a Lewis acid catalyst like aluminum chloride. The yield can be optimized by careful control of reaction conditions and purification methods.

What industries use 2,4-Diphenyl-1H-imidazole (CAS: 670-83-7)?

2,4-Diphenyl-1H-imidazole (CAS: 670-83-7) finds applications in pharmaceuticals, where it serves as a precursor for the synthesis of medicinal compounds. It is also used in the polymer industry for the modification of polymer properties and in the development of sensors due to its unique molecular structure. Additionally, it plays a role in the semiconductor industry as a dopant material.

What precautions should be taken when handling 2,4-Diphenyl-1H-imidazole (CAS: 670-83-7)?

When handling 2,4-Diphenyl-1H-imidazole (CAS: 670-83-7), it is important to follow safety guidelines. Use personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin and eye contact. Ensure that all work is conducted in a well-ventilated area or a fume hood. In the event of a spill, immediately clean it up according to the Material Safety Data Sheet (MSDS/SDS) guidelines.