2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine

Basic Information

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CAS Number

66356-53-4

Molecular Formula

C10H18N2OS

Molecular Weight

214.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Liquid

Boiling Point

106°C/0.1mmHg

Density

1.094

Flash Point

130.9 °C

Refractive Index

1.5300 to 1.5340

SMILES

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CN(C)CC1=CC=C(O1)CSCCN

InChI

InChI=1S/C10H18N2OS/c1-12(2)7-9-3-4-10(13-9)8-14-6-5-11/h3-4H,5-8,11H2,1-2H3

InChIKey

JFGCGQJHMUYGLU-UHFFFAOYSA-N

LogP

2.23340

Complexity

155

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-(2-dimethylaminomethyl-5-furylmethylthio)ethylamine
RANITIDINE HYDROCHLORIDE IMPURITY B [EP IMPURITY]
2-[((5-[(Dimethylamino)methyl]-2-furyl)methyl)sulfanyl]ethanamine #
BDBM50158372
(5-dimethylaminomethyl-2-furylmethylthio]ethylamine
2-((5-((dimethylamino)methyl)furan-2-yl)methylthio)ethanamine
EC 266-330-4
2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethanamine
AKOS015897325
2-[[[5-(Dimethylamino) methyl-2-furanyl]methyl]thio]ethanamine
5-[(2-aminoethyl)-thiomethyl]-N,N-di-methyl-2-furanmethanamine
NS00004694
D4749
2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethylamine
2-(((5-((DIMETHYLAMINO)METHYL)FURAN-2-YL)METHYL)SULFANYL)ETHANAMINE
2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethanamine? (Ranitidine Impurity
5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-furanmethanamine
SR-01000944863
2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]-ethylamine
2-[5-(dimethylaminomethyl)-2-furanylmethylthio]ethylamine
66356-53-4
2-[[5-[(dimethylamino)methyl]furfuryl]thio]ethylamine
2-[[[5-[(Dimethylamino)methyl]-2-furyl]methyl]thio]ethylamine
?5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furfurylamine
2-{[5-Dimethylamino)methylfuryl]thio}ethylamine
AS-36001
2-[(5-dimethylaminomethylfuran-2-yl)methylthio]ethylamine
AM804206
Q27289060
2-[[5-[(dimethylamino)methyl]-furfuryl]thio]ethylamine
5-[[(2-aminoethyl)thio]methyl]N,N-dimethylfuranmethanamine

MDL Number

MFCD00277202

Customs Code

2932190090

FAQ

What are the physical and chemical properties of 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine (CAS: 66356-53-4)?

2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine is a colorless or white crystalline solid with a molecular weight of approximately 304.4 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly towards nucleophilic substitution reactions and reductions.

How is 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine (CAS: 66356-53-4) typically synthesized?

2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine is usually synthesized through multi-step reactions involving the condensation of 2-bromofuran with dimethylamine, followed by the introduction of the thiourea moiety. This process often requires the use of strong bases and may involve several purification steps to achieve high purity.

What industries use 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine (CAS: 66356-53-4)?

2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine is utilized in the pharmaceutical industry for the development of certain medications due to its unique chemical structure. It also finds applications in the production of polymers and as a sensor material in chemical sensing devices.

What precautions should be taken when handling 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine (CAS: 66356-53-4)?

When handling 2-[([5-[(Dimethylamino)methyl]-2-furyl]methyl)thio]ethan-1-amine (CAS: 66356-53-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with caution; use absorbent material to contain the spill, then dispose of the material according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.