Desacetylcefotaxime

Basic Information

View in Editor

CAS Number

66340-28-1

Molecular Formula

C14H15N5O6S2

Molecular Weight

413.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

>200°C (dec.)

Density

1.92±0.1 g/cm3 (20 ºC 760 Torr),

SMILES

View in Editor

CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CO)C(=O)O

InChI

InChI=1S/C14H15N5O6S2/c1-25-18-7(6-4-27-14(15)16-6)10(21)17-8-11(22)19-9(13(23)24)5(2-20)3-26-12(8)19/h4,8,12,20H,2-3H2,1H3,(H2,15,16)(H,17,21)(H,23,24)/b18-7-/t8-,12-/m1/s1

InChIKey

FHYWAOQGXIZAAF-GHXIOONMSA-N

LogP

-1.1932999999999998

Topological Polar Surface Area

167.43999999999997 Å²

Hydrogen Bond Donor/Acceptor

5 / 11

Complexity

729

Synonyms & References

English

desacetylcefotaxime
3-Desacetyl Cefotaxime
3-DESACETYL CEFOTAXIME ,PALE YELLOW SOLID
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Deacetylcefotaxime
Cefotaxime impurity B
CEFOTAXIME IMPURITY B [EP IMPURITY]
(6R,7R)-7-{[(2Z)-1-hydroxy-2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)ethylidene]amino}-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
6E65O1Y1P8
(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CEFOTAXIME SODIUM IMPURITY B [EP IMPURITY]
3-DESACETYLCEFOTAXIME
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(hydroxymethyl)-8-oxo-, (6R-(6alpha,7beta(Z)))-
CS-0090612
SCHEMBL5679450
66340-28-1
UNII-6E65O1Y1P8
(6R,7R)-7-(((2Z)-2-(2-AMINOTHIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL)AMINO)-3-(HYDROXYMETHYL)-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID
Desacetylcefotaxime
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(hydroxymethyl)-8-oxo-, (6R,7R)-
5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2-AMINO-4-THIAZOLYL)(METHOXYIMINO)ACETYL)AMINO)-3-(HYDROXYMETHYL)-8-OXO-, (6R-(6.ALPHA.,7.BETA.(Z)))-
5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2Z)-2-(2-AMINO-4-THIAZOLYL)-2-(METHOXYIMINO)ACETYL)AMINO)-3-(HYDROXYMETHYL)-8-OXO-, (6R,7R)-
HY-126129
DEACETYLCEFOTAXIME [USP IMPURITY]

MDL Number

MFCD28899106

FAQ

What regulatory guidelines apply to Desacetylcefotaxime (CAS: 66340-28-1)?

Desacetylcefotaxime (CAS: 66340-28-1) is subject to various regulatory guidelines including GHS for chemical hazards, REACH regulations for registration, evaluation, authorization, and restriction of chemicals in the European Union, and FDA/EPA requirements for drug manufacturing and environmental protection. Compliance with these guidelines is essential for safe handling and distribution.

Are there alternatives to Desacetylcefotaxime (CAS: 66340-28-1) in synthesis?

Yes, alternatives to Desacetylcefotaxime include other cephalosporin derivatives such as cefuroxime and ceftriaxone. These compounds are often used in synthesis as they share similar pharmacological properties and can serve as effective substitutes in various applications.

What is the market or research trend for Desacetylcefotaxime (CAS: 66340-28-1)?

The market for Desacetylcefotaxime is driven by ongoing research in antibiotic development. Trends indicate an increased focus on resistance management and the search for novel cephalosporin derivatives with enhanced efficacy. The compound is also being studied for potential applications in treating respiratory and urinary tract infections.

How should waste containing Desacetylcefotaxime (CAS: 66340-28-1) be handled?

Waste containing Desacetylcefotaxime (CAS: 66340-28-1) should be collected in appropriate containers and disposed of according to local regulations. Incineration at high temperatures or professional waste disposal services are recommended to ensure complete destruction and prevent environmental contamination. Proper labeling and documentation of waste handling processes are also necessary.