Phenolphthalein anilide

Basic Information

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CAS Number

6607-41-6

Molecular Formula

C26H19NO3

Molecular Weight

393.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

610.2°C at 760 mmHg

Density

1.338

Flash Point

322.8°C

Refractive Index

1.707

SMILES

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C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3C2(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O

InChI

InChI=1S/C26H19NO3/c28-21-14-10-18(11-15-21)26(19-12-16-22(29)17-13-19)24-9-5-4-8-23(24)25(30)27(26)20-6-2-1-3-7-20/h1-17,28-29H

InChIKey

YBLBHSSRHHJKEK-UHFFFAOYSA-N

LogP

5.050100000000004

Topological Polar Surface Area

60.77000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

577

Synonyms & References

English

3,3-Bis(4-hydroxyphenyl)-2-phenyl-1-isoindolinone
4H-3,1-BENZOXAZIN-4-ONE, 2-PHENYL-
H-170
Bentranil
ST015578
2-phenyl-3,3-bis(p-phenol)phthalimidine
para,para-PPPBP
2-phenyl-4H-benzo[d][1,3]oxazine-4-one
2-phenyl-4-H-benzo[d][1,3]oxazin-4-one
3,3-bis-(4-hydroxy-phenyl)-2-phenyl-isoindolin-1-one
Linarotox
Linurotox
2-phenylbenzoxazinone
2-phenyl-3,3-bis(4-hydroxyphenyl)phthalimidine
Phenolphthalein-anilid
2-phenyl-1,2-dihydro-4H-3,1-benzoxazin-4-one
2-phenyl-4H-3,1-benzoxazin-4-one
2-Phenyl-3,1-benzoxazinone-(4)
2-phenyl-1,2-dihydro-4H-3,1-benzo
Phenolphthalein anilide
3,3-bis(4-hydroxyphenyl)-2-phenylisoindolin-1-one
BAS 00431541
YBLBHSSRHHJKEK-UHFFFAOYSA-N
N-Phenyl Phenolphthalein Bisphenol
BDBM176756
STK838406
ST50229206
US9688816, 3
3,3-bis(4-hydroxyphenyl)-2-phenylisoindol-1-one
Isoindol-1-one, 3,3-bis(4-hydroxyphenyl)-2-phenyl-2,3-dihydro-
3,3-Bis-(4-hydroxy-phenyl)-2-phenyl-2,3-dihydro-isoindol-1-one

MDL Number

MFCD00344843

FAQ

What are the physical and chemical properties of Phenolphthalein anilide (CAS: 6607-41-6)?

Phenolphthalein anilide (CAS: 6607-41-6) is a white crystalline powder with a molecular weight of approximately 322.35 g/mol. It is practically insoluble in water but soluble in organic solvents such as ethanol and acetone. Chemically, it is a weak base that can undergo acid-base reactions, making it useful in pH indicators and various analytical applications.

How is Phenolphthalein anilide (CAS: 6607-41-6) typically synthesized?

Phenolphthalein anilide is typically synthesized by the reaction of phenolphthalein with aniline in the presence of a suitable base, such as sodium hydroxide. The process involves condensation followed by acidification to obtain the desired product. The yield and selectivity are generally high, making this a reliable method for industrial production.

What industries use Phenolphthalein anilide (CAS: 6607-41-6)?

Phenolphthalein anilide (CAS: 6607-41-6) is primarily used in the pharmaceutical industry as a pH indicator in titrations and assays. It is also utilized in the manufacturing of dyes and pigments, in the production of certain polymers, and in the development of sensors and semiconductors.

What precautions should be taken when handling Phenolphthalein anilide (CAS: 6607-41-6)?

When handling Phenolphthalein anilide (CAS: 6607-41-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a well-ventilated area and use a fume hood during handling. In case of spills, clean up with care using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.