Imidazo[1,2-a]pyridine-7-carboxylic acid

Basic Information

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CAS Number

648423-85-2

Molecular Formula

C8H6N2O2

Molecular Weight

162.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

309.3±22.0℃ at 760 mmHg

SMILES

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C1=CN2C=CN=C2C=C1C(=O)O

InChI

InChI=1S/C8H6N2O2/c11-8(12)6-1-3-10-4-2-9-7(10)5-6/h1-5H,(H,11,12)

InChIKey

TUKDVVKJZVLVTD-UHFFFAOYSA-N

LogP

1.0324999999999998

Topological Polar Surface Area

54.599999999999994 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

196

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

AM20061405
EN300-102614
Imidazo[1,2-a]pyridine-7-carboxylicacid
SCHEMBL557414
TUKDVVKJZVLVTD-UHFFFAOYSA-N
FT-0647228
A834899
Imidazo[1,2-a]pyridine-7-carboxylic acid, AldrichCPR
BP-20226
648423-85-2
Imidazo[1,2-a]pyridine-7-carboxylic acid
7-imidazo[1,2-a]pyridinecarboxylic acid
PB29686
MFCD09834781
CS-0049334
AKOS006344988
Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI)
SY016704
J-521503
DTXSID60593145
HE-0336

MDL Number

MFCD09834781

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Imidazo[1,2-a]pyridine-7-carboxylic acid (CAS: 648423-85-2)?

Imidazo[1,2-a]pyridine-7-carboxylic acid is a solid with a crystalline form. Its molecular weight is approximately 215.2 g/mol. It has limited water solubility, making it sparingly soluble in water. This compound is relatively stable but can react with strong acids or bases. It displays acidity due to the carboxylic acid functional group.

How is Imidazo[1,2-a]pyridine-7-carboxylic acid (CAS: 648423-85-2) typically synthesized?

Imidazo[1,2-a]pyridine-7-carboxylic acid is typically synthesized through a multi-step process involving the condensation of 1H-imidazo[1,2-a]pyridine and acetic anhydride, followed by amination. This process yields a high purity product with good selectivity and yield. Commonly used catalysts include phosphoric acid.

What industries use Imidazo[1,2-a]pyridine-7-carboxylic acid (CAS: 648423-85-2)?

Imidazo[1,2-a]pyridine-7-carboxylic acid is used in the pharmaceutical industry for its potential as a medicinal compound. It also finds applications in the development of certain sensors and as a precursor in the synthesis of other organic compounds. Its use in the polymer industry is limited but may be explored for specific applications.

What precautions should be taken when handling Imidazo[1,2-a]pyridine-7-carboxylic acid (CAS: 648423-85-2)?

When handling Imidazo[1,2-a]pyridine-7-carboxylic acid, wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. If a spill occurs, handle it in a well-ventilated area and follow the emergency procedures outlined in the Safety Data Sheet (SDS). Ensure proper ventilation during use and avoid inhalation of dust or fumes.