1-Chloro-2-naphthol

Basic Information

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CAS Number

633-99-8

Molecular Formula

C10H7ClO

Molecular Weight

178.62 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

66.0 to 70.0 deg-C

Boiling Point

157°C/16mmHg

Density

1.333

Flash Point

139 ºC

Refractive Index

1.684

SMILES

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OC1=CC=C2C=CC=CC2=C1Cl

InChI

InChI=1S/C10H7ClO/c11-10-8-4-2-1-3-7(8)5-6-9(10)12/h1-6,12H

InChIKey

RMSOEGBYNWXXBG-UHFFFAOYSA-N

LogP

3.1988000000000003

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

160

Safety Information

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Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1-Chloro-.beta.-naphthol
1-Chloro-2-naphthol
1-chloro-2-Naphthalenol
1-chloronaphthalen-2-ol
1-Chloro-2-hydroxynaphthalene
1-chloro-2-naphtol
1-chloro-naphthalen-2-ol
1-chloronaphthalene-2-ol
2-Naphthalenol,1-chloro
2-NAPHTHOL,1-CHLORO
chloro-2-naphthol
2-Naphthalenol, 1-chloro-
1-Chloro-beta-naphthol
2-NAPHTHOL, 1-CHLORO-
3CL4OW5YKB
RMSOEGBYNWXXBG-UHFFFAOYSA-N
NSC37026
1-chloronaphtalen-2-ol
KSC355E2H

MDL Number

MFCD00997084

FAQ

What are the physical and chemical properties of 1-Chloro-2-naphthol (CAS: 633-99-8)?

1-Chloro-2-naphthol (CAS: 633-99-8) is a crystalline solid with a molecular weight of 188.6 g/mol. It has a low solubility in water (0.2 g/100 mL at 20°C) but is more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards bases and can undergo nucleophilic substitution reactions.

How is 1-Chloro-2-naphthol (CAS: 633-99-8) typically synthesized?

1-Chloro-2-naphthol can be synthesized via the reaction of 2-naphthol with thionyl chloride in the presence of a solvent like dichloromethane. The process is selective and yields a high percentage of the desired product. Catalysts are not typically required, and the reaction is carried out at room temperature.

What industries use 1-Chloro-2-naphthol (CAS: 633-99-8)?

1-Chloro-2-naphthol is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry to improve the properties of polymers, in sensor technology for the detection of specific chemicals, and in semiconductor manufacturing for etching processes.

What precautions should be taken when handling 1-Chloro-2-naphthol (CAS: 633-99-8)?

When handling 1-Chloro-2-naphthol (CAS: 633-99-8), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with care, following the safety data sheet (SDS) guidelines, and the area should be flushed with water. Proper disposal methods should be followed as per local regulations.