2-(2,5-Dioxopyrrol-1-yl)propanoic acid

Basic Information

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CAS Number

62212-14-0

Molecular Formula

C7H7NO4

Molecular Weight

169.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CC(C(=O)O)N1C(=O)C=CC1=O

InChI

InChI=1S/C7H7NO4/c1-4(7(11)12)8-5(9)2-3-6(8)10/h2-4H,1H3,(H,11,12)

InChIKey

MDNSLPICAWKNAG-UHFFFAOYSA-N

LogP

-0.6154999999999999

Topological Polar Surface Area

74.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

263

Synonyms & References

English

2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid
2-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID
2-(2,5-dioxopyrrol-1-yl)propanoic acid
N-MALEONYL-(S)-ALANINE
2-(2,5-dioxoazolinyl)propanoic acid
2-maleimido-2-methyl acetic acid
AC1L817Z
CTK7I4600
maleimido propionic acid
maleimido-propionic acid
NSC266056
SBB010500
ST090209
SureCN43717
2,5-dioxo-alpha-methyl-3-pyrroline-1-acetic acid
2-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)propanoicacid
DTXSID00313041
AKOS000142495
2-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)propanoic acid
2-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-propionic acid
MDNSLPICAWKNAG-UHFFFAOYSA-N
maleimidopropionic acid
62212-14-0
CS-0358505
SCHEMBL43717
NSC-266056

MDL Number

MFCD00460983

FAQ

What are the physical and chemical properties of 2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0)?

2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0) is a white crystalline solid with a molecular weight of approximately 148.11 g/mol. It is slightly soluble in water and has a pKa of around 4.5. This compound is reactive, particularly under acidic conditions, and is known for its ability to form salts and esters. It is often used in organic synthesis and chemical research due to its versatile reactivity.

How is 2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0) typically synthesized?

2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0) can be synthesized through a multi-step process that includes the preparation of 2,5-dioxopyrrolidine followed by its condensation with propionic acid. Common solvents used include dichloromethane and acetic anhydride. The reaction is typically catalyzed by sulfuric acid, and the yield can be improved through careful control of reaction conditions and purification techniques.

What industries use 2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0)?

2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0) is primarily used in pharmaceuticals, where it serves as a precursor in the synthesis of various drugs. It also finds applications in the polymer industry for the development of functional polymers, in sensors for its ability to bind to specific analytes, and in semiconductors for its use in organic electronic devices.

What precautions should be taken when handling 2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0)?

When handling 2-(2,5-Dioxopyrrol-1-yl)propanoic acid (CAS: 62212-14-0), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed emergency procedures and storage recommendations.