4-Dimethylaminophenol

Basic Information

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CAS Number

619-60-3

Molecular Formula

C8H11NO

Molecular Weight

137.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

138-141 ºC

Boiling Point

260 ºC

Density

1.089

Flash Point

136 ºC

Refractive Index

1.5560 (estimate)

SMILES

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CN(C)C1=CC=C(C=C1)O

InChI

InChI=1S/C8H11NO/c1-9(2)7-3-5-8(10)6-4-7/h3-6,10H,1-2H3

InChIKey

JVVRCYWZTJLJSG-UHFFFAOYSA-N

LogP

1.4582

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

95.4

Synonyms & References

English

4-(Dimethylamino)phenol
Phenol, 4-(dimethylamino)-
4-(N,N-dimethylamino)phenol
N,N-Dimethyl-4-aminophenol
N,N-Dimethyl-p-hydroxyaniline
p-(Dimethylamino)phenol
p-Hydroxy-N,N-dimethylaniline
HY-34154
Z137981254
MB02001
AE-562/43286954
4(Dimethylamino)phenol
DTXSID70210932
NS00004880
619-60-3
EINECS 210-604-8
N,NDimethylphydroxyaniline
4DMAP
N,NDimethyl4aminophenol
phenol, 4-dimethylamino-
p(Dimethylamino)phenol
4-Dimethylaminophenol
MFCD01707548
X387L5559O
SCHEMBL224308
4-Dimethylamino-phenol
CHEMBL3707216
AKOS006220509
PARA-DIMETHYLAMINOPHENOL
Phenol, 4-(dimethylamino)-(9CI)
DB13549

MDL Number

MFCD01707548

FAQ

What are the physical and chemical properties of 4-Dimethylaminophenol (CAS: 619-60-3)?

4-Dimethylaminophenol (CAS: 619-60-3) is a white crystalline solid with a molecular weight of 139.18 g/mol. It has a low solubility in water (1.2 g/100 mL at 20°C) and a high solubility in organic solvents like ethanol and acetone. The compound is relatively stable but can react with acidic or basic compounds. It has a pKa of approximately 8.3 and is commonly used in organic synthesis due to its basicity and reactivity.

How is 4-Dimethylaminophenol (CAS: 619-60-3) typically synthesized?

4-Dimethylaminophenol (CAS: 619-60-3) is typically synthesized by the reaction of aniline with dimethyl carbonate in the presence of a base such as sodium hydroxide. The reaction is carried out at room temperature, and the yield is around 70-80%. This method provides good selectivity and is commonly used in industrial settings for the production of 4-Dimethylaminophenol.

What industries use 4-Dimethylaminophenol (CAS: 619-60-3)?

4-Dimethylaminophenol (CAS: 619-60-3) is primarily used in the pharmaceutical industry due to its ability to act as a precursor in the synthesis of various drugs. It is also used in the production of dyes, as a chemical intermediate in semiconductor manufacturing, and in the development of sensors. Its versatile functionality makes it an important compound in multiple industries.

What precautions should be taken when handling 4-Dimethylaminophenol (CAS: 619-60-3)?

When handling 4-Dimethylaminophenol (CAS: 619-60-3), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. If a spill occurs, it should be cleaned up immediately using appropriate safety measures. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.