4-Methylbenzamide

Basic Information

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CAS Number

619-55-6

Molecular Formula

C8H9NO

Molecular Weight

135.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

161-163 °C

Boiling Point

248.86°C (rough estimate)

Density

1.1031 (rough estimate)

Refractive Index

1.5635 (rough estimate)

SMILES

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CC1=CC=C(C=C1)C(=O)N

InChI

InChI=1S/C8H9NO/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3,(H2,9,10)

InChIKey

UHBGYFCCKRAEHA-UHFFFAOYSA-N

LogP

1.0939200000000002

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

125

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

Mettler-Toledo Calibration substance ME 30130597, p-Toluamide, traceable to primary standards (LGC)
TOLUAMIDE, P-
4-Methyl-benzamide
SB66846
4-toluamide
AKOS002271150
p-Toluamide, 99%
DTXSID2060705
4-Methylbenzamide
SW7
CHEMBL3247924
CLADRIBINE IMPURITY F [EP IMPURITY]
p-Toluamide
EINECS 210-600-6
p-methyl benzamide
Cladribine Impurity F
CS-0071610
Benzamide, 4-methyl-
NS00034864
SCHEMBL76475
AM9809
BS-3776
T1257
p-Methylbenzamide
MFCD00008002
619-55-6
CHEBI:191154
InChI=1/C8H9NO/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3,(H2,9,10
N0V326V2F5
NSC2163
FT-0632592

MDL Number

MFCD00008002

Customs Code

2924299090

FAQ

What regulatory guidelines apply to 4-Methylbenzamide (CAS: 619-55-6)?

4-Methylbenzamide (CAS: 619-55-6) falls under various regulatory guidelines. It is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a skin irritant. In Europe, it is regulated under REACH, requiring registration for quantities above one tonne per year. In the US, it is subject to FDA and EPA regulations for industrial and commercial use. Detailed safety data sheets (SDS) should be prepared and maintained for workplace and environmental safety.

Are there alternatives to 4-Methylbenzamide (CAS: 619-55-6) in synthesis?

Alternatives to 4-Methylbenzamide (CAS: 619-55-6) in synthesis include other aromatic amines such as aniline, p-toluidine, or other substituted benzamides. These can serve as viable substitutes depending on specific reaction conditions and desired product properties. The choice of alternative often depends on the availability, cost, and reactivity of the substituent groups.

What is the market or research trend for 4-Methylbenzamide (CAS: 619-55-6)?

The market for 4-Methylbenzamide (CAS: 619-55-6) is driven by its use as a precursor in pharmaceuticals and agrochemicals. Research trends focus on its application in the development of new drugs and pesticides. Recent studies highlight its role in synthesizing active pharmaceutical ingredients (APIs) and as a component in formulation development. The trend shows a steady demand with potential for growth in emerging therapeutic areas and crop protection.

How should waste containing 4-Methylbenzamide (CAS: 619-55-6) be handled?

Waste containing 4-Methylbenzamide (CAS: 619-55-6) should be collected in appropriate containers and stored in a well-ventilated area away from incompatible materials. Incineration or professional waste disposal services should be utilized for final disposal. Environmental precautions include proper containment to prevent soil and water contamination. Compliance with local environmental regulations is essential to ensure safe and sustainable waste management practices.