Trans-L-Diaminocyclohexane Oxalatoplatinum

Basic Information

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CAS Number

61825-94-3

Molecular Formula

C8H14N2O4Pt

Molecular Weight

397.29 g/mol

EINECS

621-248-1

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

285-300°C

Water Solubility

Soluble in water with heating and/or sonication

Specific Rotation

+74.5-78.0 (D/20)(c=0.5,H2O)

SMILES

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O=C1O[Pt]OC1=O.NC1CCCCC1N

InChI

InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2

InChIKey

ZROHGHOFXNOHSO-UHFFFAOYSA-L

LogP

-0.7861

Topological Polar Surface Area

104.64 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

124

Safety Information

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GHS Hazard Pictograms

H315

H317

H319

H335

H351

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H351 Suspected of causing cancer
Carcinogenicity

Hazard Class

Class 6.1(a) Class 6.1(a)

Storage Conditions

2-8°C

Stability

Stable. Store cool. Incompatible with oxidizing agents.

Sensitiveness

heat-sensitive

Toxicity

LD50 intraperitoneal in mouse: 19800ug/kg

RTECS

TP2275850

Synonyms & References

English

Oxaliplatin
L-OHP
[SP-4-2-(1R-TRANS)]-(1,2-CYCLOHEXANEDIAMINE-N,N')[ETHANEDIOATA(2-)-O,O']PLATINUM
trans-l-diaminocyclohexane oxalatoplatinum
(1,2-cyclohexanediamine-n,n’)(ethanedioato(2-)-o,o’)-platinu(sp-4-2-(1r-tr
1-ohp
oxalato(1r,2r-cyclohexanediammine)platinum(ii)
oxalatoplatin
oxalatoplatinum
Oxaliplatin DMF
Dacplat
Elocatin
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N′)[ethanedioata(2--)-O,O’]platinum
(trans-1,2-Cyclohexanediamine)oxalatoplatinum(II)
Eloxatin (TN)
Oxaliplatin (JAN/USAN/INN)
Oxaliplatin (Eloxatin)
s1224
SW219151-1
O0372
D01790
AB01568250_01
15171-
[(1R,2R)-1,2-cyclohexanediamine-N,N']][oxalato (2-)-O,O']]platinum
OXALIPLATIN
[SP-4-2-(1R-trans)]-(1，2-Cyclohexanediamine-N，N，)[ethanedioato(2-)-O，O’Jplatinum

MDL Number

MFCD23381677

EC Number

621-248-1

Customs Code

28439000

FAQ

What is Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3)?

Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3) is a platinum-based coordination compound. It consists of a platinum(II) ion coordinated with oxalate ligands and two L-diaminocyclohexane molecules. This compound is known for its stability and is commonly used in various chemical applications, including pharmaceutical research and catalytic processes.

What are the main uses of Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3)?

Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3) is primarily used in pharmaceutical research as a precursor for developing platinum-based anticancer drugs. It also finds applications in industrial catalysts and coordination chemistry studies due to its unique structural properties and stability in different environments.

Is Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3) safe?

Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3) should be handled with care as it contains platinum, which can be toxic in high concentrations. Proper protective equipment, such as gloves and safety goggles, is recommended during handling. Safety standards for its use are typically governed by chemical safety guidelines and should follow appropriate regulatory protocols.

How should Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3) be stored?

Trans-L-Diaminocyclohexane Oxalatoplatinum (CAS: 61825-94-3) should be stored in a cool, dry, and dark place, away from moisture and light. It is best kept in a sealed container to maintain its stability and prevent degradation. Avoid exposure to air and store in a well-ventilated area to ensure safety.