(2-methoxyphenyl)methanol

Basic Information

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CAS Number

612-16-8

Molecular Formula

C8H10O2

Molecular Weight

138.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

248-250 °C

Density

1.039 g/mL at 25 °C

Water Solubility

Not miscible or difficult to mix in water. Soluble in ethanol.

Refractive Index

n20/D 1.547(lit.)

SMILES

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COC1=CC=CC=C1CO

InChI

InChI=1S/C8H10O2/c1-10-8-5-3-2-4-7(8)6-9/h2-5,9H,6H2,1H3

InChIKey

WYLYBQSHRJMURN-UHFFFAOYSA-N

LogP

1.1874999999999998

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

93.3

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1-hydroxymethyl-2-methoxy-benzene
NSC 66558
EN300-20605
Z104479146
FT-0612827
F0001-1610
W-105173
SCHEMBL17820
EINECS 210-296-5
o-Anisyl alcohol
2-Methoxybenzenemethanol
Anisyl alcohol (o-,m-,p-)
A8497
O-ANISALCOHOL
Benzenemethanol, 2-methoxy-
AKOS000120315
SY019123
BENZYL ALCOHOL, O-METHOXY-
NSC-66558
457NQ8NGCG
NT090XT6TE
(2-Methoxyphenyl)methanol #
NSC66558
(2-Methoxy-phenyl)-methanol
(2-methoxyphenyl)-methanol
2-methoxy-benzyl alcohol
2-Methoxybenzyl alcohol, 99%
MFCD00004611
1-hydroxymethyl-2-methoxybenzene
612-16-8
o-Methoxybenzyl alcohol

MDL Number

MFCD00004611

Customs Code

29094990

FAQ

What are the physical and chemical properties of (2-methoxyphenyl)methanol (CAS: 612-16-8)?

(2-methoxyphenyl)methanol is a colorless to light yellow liquid with a molecular weight of approximately 144.17 g/mol. It has a pKa of around 14.5 and is slightly soluble in water but miscible with a variety of organic solvents. It is relatively stable under normal conditions but can react with strong acids or bases. The compound is often used in organic synthesis due to its reactivity and solubility properties.

How is (2-methoxyphenyl)methanol (CAS: 612-16-8) typically synthesized?

(2-Methoxyphenyl)methanol is typically synthesized via the reduction of 2-methoxybenzaldehyde. This can be achieved using hydrogen in the presence of a catalyst like palladium on carbon. The reaction is selective and provides high yields. Other methods include the direct methylation of hydroxybenzaldehyde followed by reduction.

What industries use (2-methoxyphenyl)methanol (CAS: 612-16-8)?

(2-Methoxyphenyl)methanol is used in the pharmaceutical industry for the synthesis of certain drug molecules, in the polymer industry as a monomer, in the chemical industry for the production of various organic compounds, and in the sensor industry for its use in detecting specific chemicals. Its versatility makes it a valuable intermediate in multiple fields.

What precautions should be taken when handling (2-methoxyphenyl)methanol (CAS: 612-16-8)?

When handling (2-methoxyphenyl)methanol (CAS: 612-16-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be cleaned up carefully, and the material safety data sheet (MSDS) should always be consulted for specific handling instructions.