1H-Pyrazol-5-ol

Basic Information

View in Editor

CAS Number

60456-92-0

Molecular Formula

C3H4N2O

Molecular Weight

84.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

OC1=NNC=C1

InChI

InChI=1S/C3H4N2O/c6-3-1-2-4-5-3/h1-2H,(H2,4,5,6)

InChIKey

XBYRMPXUBGMOJC-UHFFFAOYSA-N

LogP

0.1152999999999999

Topological Polar Surface Area

48.910000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1H-Pyrazol-3-ol
1H-Pyrazol-3(2H)-one
2H-Pyrazol-3-ol
5-hydroxy-pyrazole
1H-Pyrazol-5-ol
1,2-Dihydro-3H-pyrazol-3-one
3-Hydroxypyrazole
Pyrazolinone
5-hydroxypyrazole
1,2-dihydropyrazol-3-one
Hydroxypyrazole
pyrazole-3-ol
Pyrazol-3-ol
Pyrazol-5-ol
1h-pyrazole-3-ol
NSC520837
3-Pyrazolin-5-one
Pyrazolone, dihydro-
PubChem23624
PubChem23482
3-hydroxy-1H-pyrazole
5-Hydroxy-1H-pyrazole
1H-Pyrazolol (9CI)
1H-Pyrazol-3(2H);-one
3H-Pyrazol-3-one, dihyd

MDL Number

MFCD20527386

FAQ

What regulatory guidelines apply to 1H-Pyrazol-5-ol (CAS: 60456-92-0)?

1H-Pyrazol-5-ol (CAS: 60456-92-0) should comply with GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for classification and labeling. In the EU, it falls under REACH regulations, requiring manufacturers and importers to register chemicals. For the USA, the Environmental Protection Agency (EPA) and Food and Drug Administration (FDA) have specific reporting and handling requirements for chemical substances. Additionally, local and regional regulations should be consulted for comprehensive compliance.

Are there alternatives to 1H-Pyrazol-5-ol (CAS: 60456-92-0) in synthesis?

There are several alternatives to 1H-Pyrazol-5-ol (CAS: 60456-92-0) in synthesis, including other pyrazoles and related heterocycles. Common substitutes include 1H-Pyrazol-3-ol and 1H-Pyrazol-4-ol. Alternative reagents such as sodium hydroxide or potassium hydroxide can also be used as precursors in the synthesis of pyrazoles.

What is the market or research trend for 1H-Pyrazol-5-ol (CAS: 60456-92-0)?

The market for 1H-Pyrazol-5-ol (CAS: 60456-92-0) is driven by its use in pharmaceuticals, agrochemicals, and research. Recent trends show increased interest in its application as a bioisostere in drug discovery. Research is also focusing on its synthesis and reactivity, with a growing body of literature exploring its use in polymer synthesis and catalysis. Market trends indicate a steady demand, with potential for growth in emerging applications.

How should waste containing 1H-Pyrazol-5-ol (CAS: 60456-92-0) be handled?

Waste containing 1H-Pyrazol-5-ol (CAS: 60456-92-0) should be collected in appropriate sealed containers and disposed of according to local regulations. Incineration is a common method, but professional waste disposal services may be necessary for proper handling. Environmental protection measures should include preventing spills and ensuring proper ventilation during handling. Always consult local guidelines for specific disposal procedures.