Ercalcitriol | CAS No. 60133-18-8

Ercalcitriol

Basic Information

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CAS Number

60133-18-8

Molecular Formula

C28H44O3

Molecular Weight

428.66 g/mol

Chemical Classification

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

No data available

Melting Point

No data available

Boiling Point

577.655 ℃ at 760 mmHg

Density

1.066

Refractive Index

1.554

SMILES

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CC(C=CC(C)C(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C

InChI

InChI=1S/C28H44O3/c1-18(9-10-19(2)27(4,5)31)24-13-14-25-21(8-7-15-28(24,25)6)11-12-22-16-23(29)17-26(30)20(22)3/h9-12,18-19,23-26,29-31H,3,7-8,13-17H2,1-2,4-6H3/b10-9+,21-11+,22-12-/t18-,19+,23-,24-,25+,26+,28-/m1/s1

InChIKey

ZGLHBRQAEXKACO-XJRQOBMKSA-N

LogP

5.726700000000008

Topological Polar Surface Area

60.69 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

758

Safety Information

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GHS Hazard Pictograms

H301

H311

H331

H361

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H331 Toxic if inhaled
Acute toxicity, inhalation

H361 Suspected of damaging fertility or the unborn child
Reproductive toxicity

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

1alpha,25-Dihydroxycalciferol
1.ALPHA.,25-DIHYDROXYERGOCALCIFEROL
DTXSID90429509
1,3-Cyclohexanediol, 4-methylene-5-((2E)-2-((1R,3aS,7aR)-octahydro-1-((1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl)-7a-methyl-4H-inden-4-ylidene)ethylidene)-, (1R,3S,5Z)-
HY-32350
1
o-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol
1?,25-Dihydroxyvitamin D2
AKOS024457904
1.alpha.,25-dihydroxyvitamin d2
UNII-5RWP08OQ36
1,25-Dihydroxy vitamin D
1 alpha ,25-Dihydroxyvitamin D2
1(ALPHA) 25-DIHYDROXYVITAMIN D2*
CHEMBL4303615
CHEBI:86320
Q27159080
LMST03010040
CS-0394
9,10-SECOERGOSTA-5,7,10(19),22-TETRAENE-1,3,25-TRIOL, (1.ALPHA.,3.BETA.,5Z,7E,22E)-
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
25-Hydroxy Doxercalciferol
1a,25-Dihydroxyvitamin D2
RO-17-6218
1alpha,25-Dihydroxyvitamin D2, >=97.0% (sum of vitamin and previtamin, HPLC)
1a,25-Dihydroxycalciferol
60133-18-8
1?,25-Dihydroxy Vitamin D2
A869040
5RWP08OQ36
AS-75822

MDL Number

MFCD00869499

FAQ

What is Ercalcitriol (CAS: 60133-18-8)?

Ercalcitriol (CAS: 60133-18-8) is a synthetic analog of vitamin D3, specifically 1,25-dihydroxyvitamin D3. It is a white or almost white crystalline powder with a molecular formula of C28H44O3 and a molecular weight of 436.66. Ercalcitriol is highly soluble in organic solvents and slightly soluble in water.

What are the main uses of Ercalcitriol (CAS: 60133-18-8)?

Ercalcitriol (CAS: 60133-18-8) is primarily used as a medication to treat and prevent hypocalcemia, a condition characterized by low levels of calcium in the blood. It is also used in the treatment of osteoporosis and for the prevention of renal bone disease. Additionally, it is used in the management of hyperparathyroidism associated with kidney disease.

Is Ercalcitriol (CAS: 60133-18-8) safe?

Ercalcitriol (CAS: 60133-18-8) is generally considered safe when used as directed by a healthcare provider. However, it can cause side effects such as hypercalcemia, hypercalciuria, and hyperphosphatemia. It is important to follow recommended dosage guidelines and regularly monitor blood levels to prevent adverse effects.

How should Ercalcitriol (CAS: 60133-18-8) be stored?

Ercalcitriol (CAS: 60133-18-8) should be stored in a cool, dry place, protected from light and moisture. It is recommended to keep the medication in its original packaging or a suitable, tightly sealed container. The storage temperature should not exceed 25°C (77°F). Avoid storing it in areas with high humidity or direct sunlight to maintain its efficacy and safety.