1,3-Dihydro-2H-indol-2-one

Basic Information

View in Editor

CAS Number

59-48-3

Molecular Formula

C8H7NO

Molecular Weight

133.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

125.0 to 130.0 deg-C

Boiling Point

227°C/23mmHg

Flash Point

194-196°C/17mm

Solubility

9.1g/l

Refractive Index

1.5282 (estimate)

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

View in Editor

C1C2=CC=CC=C2NC1=O

InChI

InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)

InChIKey

JYGFTBXVXVMTGB-UHFFFAOYSA-N

LogP

1.1812

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

155

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

STK336410
2-Oxindoline
AB00523
EINECS 200-429-5
1,3-Dihydro-2H-indol-2-one #
2,3-Dihydroindole-2-one
indolin 2-one
SCHEMBL9305641
AB7349
SCHEMBL4787148
2(1H,3H)indolone
NSC-274863
5-21-08-00007 (Beilstein Handbook Reference)
BP-12514
2H-Indol-2-one, 1,3-dihydro-
CG-0513
BB 0257524
DICLOFENAC SODIUM IMPURITY E [EP IMPURITY]
2-Ketoindoline
CX1001
AH-034/32845032
2-Oxindole pound>>Diclofenac Impurity E
Indolin-2-one
BDBM50434120
STR01316
2-OXOINDOLE
2,3-Dihydroindol-2-one
Oxindole (2-Indolone)
2-Oxindole, 97%
EN300-20422
DICLOFENAC POTASSIUM IMPURITY I [EP IMPURITY]

MDL Number

MFCD00005711

Customs Code

29337900

FAQ

What is 1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3)?

1,3-Dihydro-2H-indol-2-one, with the CAS number 59-48-3, is a heterocyclic organic compound belonging to the indole family. It has the chemical formula C8H7NO and is characterized by its cyclic structure containing a five-membered ring fused to a six-membered ring. This compound is known for its use as an intermediate in the synthesis of various pharmaceuticals and organic materials.

What are the main uses of 1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3)?

1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3) is primarily used as a building block in the production of pharmaceuticals, particularly in the development of drugs targeting neurological and psychiatric conditions. It also finds applications in the synthesis of organic dyes, polymers, and other chemical compounds. Its versatility makes it valuable in research and industrial settings.

Is 1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3) safe?

1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3) is generally considered safe when handled properly, but it may have potential toxicity if ingested or inhaled in large quantities. It is important to follow safety guidelines, use appropriate personal protective equipment (PPE), and ensure proper ventilation during handling. Safety standards for this compound are typically in line with those for organic chemicals used in industrial and research environments.

How should 1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3) be stored?

1,3-Dihydro-2H-indol-2-one (CAS: 59-48-3) should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is recommended to keep it in a sealed container, preferably made of glass or high-density polyethylene, to maintain stability and prevent degradation. Proper storage helps ensure its longevity and safety in handling.