5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline

Basic Information

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CAS Number

5840-01-7

Molecular Formula

C11H11N

Molecular Weight

157.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

84.0 to 88.0 deg-C

Boiling Point

318.4℃ at 760 mmHg

Flash Point

146.349 °C

Refractive Index

1.656

SMILES

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C1CC2=CC=CC3=C2N(C1)C=C3

InChI

InChI=1S/C11H11N/c1-3-9-5-2-7-12-8-6-10(4-1)11(9)12/h1,3-4,6,8H,2,5,7H2

InChIKey

QCCKSFHMARIKSK-UHFFFAOYSA-N

LogP

2.5875000000000004

Topological Polar Surface Area

4.93 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

178

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

BCP21768
EN300-3453498
DTXSID80576238
1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraene
AKOS006329426
SY024437
Lilolidine (5,6-Dihydro-4H-pyrrolo(3,2,1-ij)quinoline)
Lilolidine, 95%
5 pound not6-Dihydro-4H-pyrrolo[3 pound not2 pound not1-ij]quinoline
J-516532
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline
4H-Pyrrolo[3,2,1-ij]quinoline, 5,6-dihydro-
L0274
1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4,6,8(12)-tetraene
A915134
MFCD09841910
QCCKSFHMARIKSK-UHFFFAOYSA-N
5,6dihydro-4H-pyrolo[3,2,1-ij]quinoline
DS-2184
FT-0653200
5840-01-7
SCHEMBL1395813
AC-25058
1-azatricyclo[6.3.1.0,4,12]dodeca-2,4,6,8(12)-tetraene
CS-B1108
AMY842
Lilolidine
2,3-DIHYDRO-1H-PYRROLO[3,2,1-IJ]QUINOLINE
Lilodidine
1,7-Trimethyleneindole
G00001-Watson-Int

MDL Number

MFCD09841910

FAQ

What are the physical and chemical properties of 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline (CAS: 5840-01-7)?

5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline has a crystalline form with a molecular weight of approximately 222.22 g/mol. It is slightly soluble in water but readily soluble in organic solvents such as ethanol and acetone. Chemically, it is relatively stable but can undergo ring-opening reactions under acidic conditions. The compound exhibits basic properties due to its nitrogen-containing heterocycles.

How is 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline (CAS: 5840-01-7) typically synthesized?

5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline is usually synthesized via the condensation of 2-aminopyridine with 4-bromobenzaldehyde, followed by reduction of the resulting intermediate to form the 5,6-dihydro derivative. This process often involves the use of palladium catalysts and requires high selectivity and yield to produce the desired product.

What industries use 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline (CAS: 5840-01-7)?

5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline finds applications in the pharmaceutical industry for its potential as a bioactive compound, in the polymer industry for introducing specific chemical functionalities, and in the sensor and semiconductor industries for its electronic properties. It is also used in research and development for its structural complexity and potential bioactivity.

What precautions should be taken when handling 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline (CAS: 5840-01-7)?

When handling 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area, preferably with a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to safety data sheet (SDS) guidelines. Always refer to the current SDS for specific handling instructions and emergency procedures.