7-Chloropyrazolo[1,5-a]pyrimidine

Basic Information

View in Editor

CAS Number

58347-49-2

Molecular Formula

C6H4ClN3

Molecular Weight

153.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

96-98 ºC

Density

1.51

SMILES

View in Editor

Clc1ccnc2ccnn12

InChI

InChI=1S/C6H4ClN3/c7-5-1-3-8-6-2-4-9-10(5)6/h1-4H

InChIKey

YCZQHXPIKQHABJ-UHFFFAOYSA-N

LogP

1.3826999999999994

Topological Polar Surface Area

30.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

130

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Synonyms & References

English

7-Chloropyrazolo[1,5-a]pyrimidine
7-Chloro-pyrazolo[1,5-a]pyrimidine
Pyrazolo[1,5-a]pyrimidine, 7-chloro-
SC3201
ZLD0555
zlchem 1087
YCZQHXPIKQHABJ-UHFFFAOYSA-N
7-Chloropyrazolo[1?5-a]pyrimidine
FCH848509
7-chloranylpyrazolo[1,5-a]pyrimidine
TRA0040530
PB27621
RP01815
HP23552
AM804085
SY015735
BR
7-chloropyrazolo[1,5-a]pyrimidine

MDL Number

MFCD04035684

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 7-Chloropyrazolo[1,5-a]pyrimidine (CAS: 58347-49-2)?

7-Chloropyrazolo[1,5-a]pyrimidine is a crystalline solid with a molecular weight of approximately 196.03 g/mol. It is slightly soluble in water but soluble in common organic solvents like DMSO. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It exhibits good stability under normal storage conditions but requires protection from moisture and light.

How is 7-Chloropyrazolo[1,5-a]pyrimidine (CAS: 58347-49-2) typically synthesized?

7-Chloropyrazolo[1,5-a]pyrimidine is synthesized via various routes, commonly through the reaction of chloropyrazine and hydrazine, followed by pyrimidine ring closure. This process often involves the use of a catalyst such as an acid or base, with high selectivity and yield. Detailed procedures can be found in literature and patents.

What industries use 7-Chloropyrazolo[1,5-a]pyrimidine (CAS: 58347-49-2)?

7-Chloropyrazolo[1,5-a]pyrimidine is used in the pharmaceutical industry for developing drugs. It also finds applications in the synthesis of polymers and as a component in sensors and semiconductors due to its unique electronic and structural properties.

What precautions should be taken when handling 7-Chloropyrazolo[1,5-a]pyrimidine (CAS: 58347-49-2)?

When handling 7-Chloropyrazolo[1,5-a]pyrimidine, it is essential to wear personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for more detailed handling instructions.