Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate

Basic Information

View in Editor

CAS Number

58207-19-5

Molecular Formula

C18H36Cl2N2O6S

Molecular Weight

479.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

143°C

Boiling Point

647°C at 760 mmHg

Water Solubility

Soluble in water

Flash Point

345.1 °C

Refractive Index

143 ° (C=2, H2O)

SMILES

View in Editor

CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.O.Cl

InChI

InChI=1S/C18H33ClN2O5S.ClH.H2O/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H;1H2/t9-,10+,11-,12+,13-,14+,15+,16+,18+;;/m0../s1

InChIKey

KWMXKEGEOADCEQ-WNNJHRBUSA-N

LogP

-0.013399999999999745

Topological Polar Surface Area

133.76000000000002 Å²

Hydrogen Bond Donor/Acceptor

6 / 8

Complexity

502

Safety Information

View Safety Information

GHS Hazard Pictograms

H303

Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

Hazard Class

Class 3 Class 3

Synonyms & References

English

L-THREO-.ALPHA.-D-GALACTO-OCTOPYRANOSIDE, METHYL 7-CHLORO-6,7,8-TRIDEOXY-6-(((1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL)AMINO)-1-THIO-, MONOHYDROCHLORIDE, MONOHYDRATE,(2S-TRANS)-
D89500
Q27295770
Clindamycin hydrochloride monohydrate
METHYL 7-CHLORO-6,7,8-TRIDEOXY-6-(1-METHYL-TRANS-4-PROPYL-L-2-PYRROLIDINECARBOXAMIDO)-1-THIO-L-THREO-.ALPHA.-D-GALACTO-OCTOPYRANOSIDE MONOHYDROCHLORIDE, MONOHYDRATE
MFCD06411091
ZNC153389R
SCHEMBL7161659
Clindamycin HCl monohydrate
threo-alpha-d-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, monohydrochloride, monohydrate, (2S-trans)-
AKOS015900869
CLINDAMYCIN ALCOHOLATE
(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrate;hydrochloride
UNII-ZNC153389R
CLINDAMYCIN MONOHYDROCHLORIDE MONOHYDRATE [WHO-DD]
58207-19-5
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-l-threo-alpha-d-galacto-octopyranoside monohydrochloride, monohydrate
Clindamycin (hydrochloride monohydrate)
AS-10145
s5420
CLINDAMYCIN MONOHYDROCHLORIDE MONOHYDRATE
Clindamycin hydrochloride hydrate
CCG-269538
CLINDAMYCIN HYDROCHLORIDE MONOHYDRATE [MI]
Clindamycin alcoholate
Clindamycin Hydrochloride Monohydrate
Clindamycin hydrochloride
CLINDAMYCIN HYDROCHLORIDE HYDRATE
CLINDAMYCIN HYDROCHLORIDE, BP
USP
Clindamycin Hcl

MDL Number

MFCD06411091

FAQ

What is Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate (CAS: 58207-19-5)?

Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate is a complex organic compound used in pharmaceuticals and research. It consists of a methyl group attached to a specific sugar derivative with a unique amino acid side chain. This compound is characterized by its unique stereochemistry and functional groups, making it useful in various biological and medicinal applications.

What are the main uses of Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate (CAS: 58207-19-5)?

Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate is primarily used in pharmaceutical research and development, particularly in the synthesis of bioactive molecules and in drug discovery processes. It is also utilized in the exploration of novel chemical structures for potential therapeutic applications.

Is Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate (CAS: 58207-19-5) safe?

Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate is generally considered safe under the proper handling and storage conditions. It is important to follow safety guidelines, including the use of appropriate personal protective equipment and working in a well-ventilated area. Specific safety measures should be adhered to as outlined in Material Safety Data Sheets (MSDS).

How should Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate (CAS: 58207-19-5) be stored?

Methyl (5R)-5-[(1S,2S)-2-chloro-1-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}propyl]-1-thio-beta-L-arabinopyranoside hydrochloride hydrate should be stored in a tightly sealed container at a temperature between 15-25°C, away from direct sunlight and heat sources. It should be kept in a well-ventilated area and handled with care to prevent breakage. Storage in a cool, dry place is recommended to maintain its stability and purity.