Miltefosine | CAS No. 58066-85-6

Miltefosine

Basic Information

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CAS Number

58066-85-6

Molecular Formula

C21H46NO4P

Molecular Weight

407.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Physical State

No data available

Melting Point

232-234° (dec)

Boiling Point

No data available

Density

No data available

Flash Point

No data available

Solubility

H2O: soluble10mg/mL, clear, colorless

Vapor Pressure

No data available

SMILES

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CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C

InChI

InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3

InChIKey

PQLXHQMOHUQAKB-UHFFFAOYSA-N

LogP

6.74570

Complexity

363

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Toxicity

LD50 in rats (mg/kg): 246 orally (Muschiol)

Synonyms & References

English

EN300-7397728
CCG-40025
Fos-choline 16
hexadecylphosphocholine, miltefosine
Hexadecylphosphocholine
NS00004313
HY-13685
D 18506
2-(((Hexadecycloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium Inner Salt
hexadecyl 2-(trimethyl-lambda~5~-azanyl)ethyl hydrogen phosphate
hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
n-Hexadecylphosphorylcholine
Hexadecyl 2-(Trimethylammonio)ethyl Phosphate Hydrate
Hexadecyl Phosphorylcholine
Miltefosine (INN)
BDBM50034220
n-hexadecylphosphocholine
NCGC00095169-01
?Miltefosine
D-18506
DB09031
AKOS015914886
P01CX04
Miltefos
MILTEFOSINE [MI]
NCGC00095169-03
Miltefosinum
hexadecyl 2-(trimethylammonio)ethyl phosphate
Miltefosina (INN-Spanish)
miltefosine (hexadecylphosphocholine)
NCGC00095169-05

MDL Number

MFCD00133396

FAQ

What is Miltefosine (CAS: 58066-85-6)?

Miltefosine is an antiparasitic medication used to treat cutaneous leishmaniasis. It has a molecular formula of C21H33NO7 and is a white to off-white crystalline powder. It is lipophilic and has good solubility in organic solvents.

What are the main uses of Miltefosine (CAS: 58066-85-6)?

Miltefosine is primarily used for the treatment of cutaneous leishmaniasis. It is also being investigated for its potential use in treating other parasitic diseases such as visceral leishmaniasis and African trypanosomiasis.

Is Miltefosine (CAS: 58066-85-6) safe?

Miltefosine is generally considered safe when used under medical supervision. However, it can cause side effects such as nausea, vomiting, and diarrhea. It is important to follow the prescribed dosage and report any unusual symptoms to a healthcare provider. Handling should be done with caution to avoid skin contact and inhalation. Exposure to sunlight should be avoided, and it should be stored away from heat and light.

How should Miltefosine (CAS: 58066-85-6) be stored?

Miltefosine should be stored in a tightly sealed container at room temperature, protected from light. It should be kept at a temperature not exceeding 25°C. Ensure it is stored in a dry place away from moisture and direct sunlight. Do not store in areas with high humidity or heat, as this can affect its stability and potency. Keep out of reach of children and pets.