Avatrombopag Impurity 20

Basic Information

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CAS Number

570407-10-2

Molecular Formula

C7H5ClN2S2

Molecular Weight

216.72 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.535±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=C(SC=C1Cl)C2=CSC(=N2)N

InChI

InChI=1S/C7H5ClN2S2/c8-4-1-6(11-2-4)5-3-12-7(9)10-5/h1-3H,(H2,9,10)

InChIKey

SMBPGSKGPGBYBQ-UHFFFAOYSA-N

LogP

3.1072000000000006

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

170

Synonyms & References

English

SMBPGSKGPGBYBQ-UHFFFAOYSA-N
SCHEMBL1665356
4-(4-Chloro-2-thienyl)-2-thiazolamine
570407-10-2
EN300-1966897
BCP33145
4-(4-CHLOROTHIOPHEN-2-YL)-1,3-THIAZOL-2-AMINE
MFCD24627156
AMY30739
4-(4-Chlorothiophen-2-yl)thiazol-2-amine;2-Thiazolamine, 4-(4-chloro-2-thienyl)-
2-Thiazolamine, 4-(4-chloro-2-thienyl)-
2-amino-4-(4-chlorothiophen-2-yl)thiazole
CS-0372956
F71516
AKOS026750732
4-(4-chlorothiophen-2-yl)thiazol-2-amine
chlorothiophen-2-yl)-1,3-thiazol-2-amine
A1-04919
DTXSID70629909
4-(4-chlorothiophen-2-yl)-1,3-thiazol-2-amine
2-Amino-4-(4-chlorothiophen-2-yl)thiazole

MDL Number

MFCD24627156

FAQ

What regulatory guidelines apply to Avatrombopag Impurity 20 (CAS: 570407-10-2)?

Regulatory guidelines for Avatrombopag Impurity 20 (CAS: 570407-10-2) include GHS classification for hazardous materials, REACH regulations for registration, evaluation, authorization, and restriction of chemicals, and FDA/EPA requirements for safety and environmental protection. These guidelines ensure that the impurity is handled, stored, and disposed of safely and legally.

Are there alternatives to Avatrombopag Impurity 20 (CAS: 570407-10-2) in synthesis?

In synthesis, alternatives to Avatrombopag Impurity 20 (CAS: 570407-10-2) include using different starting materials or reagents, such as 5-(4-fluorophenyl)-N-(1-(4-methyl-1,3-benzothiazol-2-yl)-1H-1,2,3-triazol-4-yl)-1H-pyrazole-3-carboxamide, which can serve as a precursor or substitute. These alternatives help in optimizing the synthesis process and reducing impurity levels.

What is the market or research trend for Avatrombopag Impurity 20 (CAS: 570407-10-2)?

The market and research trend for Avatrombopag Impurity 20 (CAS: 570407-10-2) reflects a growing interest in the safety and purity of pharmaceutical compounds. Researchers are focusing on developing methods to minimize impurities, ensuring that Avatrombopag meets stringent quality standards. Additionally, there is a trend towards more sustainable and environmentally friendly synthesis methods, which can reduce the presence of impurities in the final product.

How should waste containing Avatrombopag Impurity 20 (CAS: 570407-10-2) be handled?

Waste containing Avatrombopag Impurity 20 (CAS: 570407-10-2) should be collected in appropriate containers, labeled with the correct hazard warnings, and stored in a secure area. For disposal, professional waste disposal services should be used, as they can ensure the waste is incinerated or treated to meet environmental protection standards. Proper documentation and permits may be required to manage and dispose of the waste safely.