Avatrombopag Impurity 38

Basic Information

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CAS Number

570403-14-4

Molecular Formula

C31H38Cl2N6O3S2

Molecular Weight

677.71 g/mol

Basic Physical Properties

Density

1.375±0.06 g/cm3(Predicted)

SMILES

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ClC1=CC(=CN=C1N1CCC(C(=O)OCC)CC1)C(NC1=NC(C2=CC(=CS2)Cl)=C(N2CCN(CC2)C2CCCCC2)S1)=O

InChI

1S/C31H38Cl2N6O3S2/c1-2-42-30(41)20-8-10-38(11-9-20)27-24(33)16-21(18-34-27)28(40)36-31-35-26(25-17-22(32)19-43-25)29(44-31)39-14-12-37(13-15-39)23-6-4-3-5-7-23/h16-20,23H,2-15H2,1H3,(H,35,36,40)

InChIKey

ZJPGKQRKCHDVOR-UHFFFAOYSA-N

LogP

7.059900000000008

pKa

3.04±0.70(Predicted)

Topological Polar Surface Area

90.9 Å²

Hydrogen Bond Donor/Acceptor

1 / 9

Complexity

967

Synonyms & References

English

1-(3-chloro-5-([4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl]carbamoyl}-2-pyridyl)piperidine-4-carboxylic acid ethyl ester
1-(3-chloro-5-{[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl]carbamoyl}-2-pyridyl)piperidine-4-carboxylic acid ethyl ester
ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate
Avatrombopag Impurity 15
4-Piperidinecarboxylic acid, 1-[3-chloro-5-[[[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl]amino]carbonyl]-2-pyridinyl]-, ethyl ester
Avatrombopag Impurity 22
Avatroposide impurities21
Ethyl 1-(3-chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylate (Avatrombopag Impurity)
Avatrapa impurity 5
Avibactam impurity 04K-Z3

FAQ

What is Avatrombopag Impurity 38 (CAS: 570403-14-4)?

Avatrombopag Impurity 38 (CAS: 570403-14-4) is a chemical compound used as an impurity in the synthesis of the medication avatrombopag, which is used to treat thrombocytopenia. It is not intended for direct use and does not have a specific chemical formula or properties distinct from its parent compound without further context.

What are the main uses of Avatrombopag Impurity 38 (CAS: 570403-14-4)?

Avatrombopag Impurity 38 (CAS: 570403-14-4) is primarily used as a by-product in the manufacturing process of avatrombopag, a medication used to increase platelet counts in patients with thrombocytopenia. It is not used independently and is not available for other applications.

Is Avatrombopag Impurity 38 (CAS: 570403-14-4) safe?

Avatrombopag Impurity 38 (CAS: 570403-14-4) is safe when handled appropriately. However, it should only be handled by trained professionals due to its role in pharmaceutical production. Proper protective measures, such as gloves and safety glasses, should be used to avoid skin or eye contact. It is not intended for direct use in humans or animals.

How should Avatrombopag Impurity 38 (CAS: 570403-14-4) be stored?

Avatrombopag Impurity 38 (CAS: 570403-14-4) should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to protect it from moisture and air. Proper storage conditions are critical to maintaining its stability and safety during storage and transportation.