4-(1-Piperazinyl)phenol

Basic Information

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CAS Number

56621-48-8

Molecular Formula

C10H14N2O

Molecular Weight

178.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

220-225 °C

Boiling Point

371.3 °C at 760 mmHg

Density

1.141

Flash Point

178.3 °C

Refractive Index

1.576

SMILES

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C1CN(CCN1)C2=CC=C(C=C2)O

InChI

InChI=1S/C10H14N2O/c13-10-3-1-9(2-4-10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2

InChIKey

GPEOAEVZTOQXLG-UHFFFAOYSA-N

LogP

0.8017999999999996

Topological Polar Surface Area

35.5 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

149

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

4-hydroxy phenylpiperazine
4-(1-piperazino)phenol
p-(1-Piperazinyl)phenol
56621-48-8
4-(piperazin-1-yl)-phenol
BDBM626043
4-Piperazinyl phenol
4-piperazin-1-yl-phenol
1-(4-Hydroxyphenyl)-piperazine
4-(1-Piperazinyl)phenol
4-piperazine-1-yl-phenol
Oprea1_539482
4-(4-hydroxyphenyl)piperazine
MFCD00066156
NS00033553
DTXSID80205197
N-(4-hydroxyphenyl)-piperazine
EINECS 260-289-6
1-(4-Hydroxyphenyl)piperazine
4-(piperazin-1-yl)phenol
A2SA24RA7S
SCHEMBL40343
EN300-17230
N-(4-Hydroxyphenyl)piperazine;4-Piperazin-1-yl-phenol;4-Piperazinophenol
F2158-0909
GPEOAEVZTOQXLG-UHFFFAOYSA-N
AKOS001044007
AC-8984
N-(4-hydroxyphenyl)piperazine
Phenol, 4-(1-piperazinyl)-
CS-W017311

MDL Number

MFCD00066156

Customs Code

2933599090

FAQ

What regulatory guidelines apply to 4-(1-Piperazinyl)phenol (CAS: 56621-48-8)?

4-(1-Piperazinyl)phenol (CAS: 56621-48-8) falls under the regulatory guidelines of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and is classified as a skin and eye irritant. It is also subject to European Union REACH regulations. In the USA, it requires FDA and EPA compliance for manufacturing, handling, and disposal.

Are there alternatives to 4-(1-Piperazinyl)phenol (CAS: 56621-48-8) in synthesis?

There are several alternatives to 4-(1-Piperazinyl)phenol (CAS: 56621-48-8) in synthesis, such as using related piperazine derivatives like 4-(1-azepan-1-yl)phenol or other phenolic compounds. These alternatives can offer similar functional properties with varying degrees of reactivity and solubility.

What is the market or research trend for 4-(1-Piperazinyl)phenol (CAS: 56621-48-8)?

The market for 4-(1-Piperazinyl)phenol (CAS: 56621-48-8) is driven by its use in pharmaceuticals and agrochemicals. Recent research trends focus on its applications in drug discovery and as a precursor in organic synthesis. Market trends suggest a steady demand with occasional fluctuations based on new applications and regulatory changes.

How should waste containing 4-(1-Piperazinyl)phenol (CAS: 56621-48-8) be handled?

Waste containing 4-(1-Piperazinyl)phenol (CAS: 56621-48-8) should be collected in appropriate containers and disposed of through professional waste disposal services. It is recommended to neutralize the waste with a suitable base before disposal to reduce environmental impact. Always adhere to local environmental protection regulations and ensure safe handling to prevent environmental contamination.