6-Maleimidocaproic Acid

Basic Information

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CAS Number

55750-53-3

Molecular Formula

C10H13NO4

Molecular Weight

211.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

86.0 to 91.0 deg-C

Water Solubility

Soluble in water, methanol, ethanol, dimethyl sulfoxide. Insoluble in ether.

SMILES

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OC(=O)CCCCCN1C(=O)C=CC1=O

InChI

InChI=1S/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15)

InChIKey

WOJKKJKETHYEAC-UHFFFAOYSA-N

LogP

0.5564

Topological Polar Surface Area

74.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

291

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Moisture Sensitive

Synonyms & References

English

6-Maleimidohexanoic acid
N-MALEOYL-6-AMINO-CAPROIC ACID
N-EPSILON-MALEIMIDOCAPROIC ACID
N-(5-CARBOXYPENTYL)MALEIMIDE
EMCA
EPSILON-MALEIMIDOCAPROIC ACID
6-MALEIMIDOCAPROIC ACID
6-Maleimidocapronic acid
6-(2,5-dioxo-2H-pyrrol-1(5H)-yl)hexanoic acid
6-Maleimidocaproic A
6-(2,5-dioxopyrrol-1-yl)hexanoic acid
N-Maleoyl-6-aminocaproic acid
2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid
6-Maleimide hexanoic acid
MCA
Maleimidocaproic acid
6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid
1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-
Maleimide-(CH2)5-COOH
1H-Pyrrole-1-hexanoicacid, 2,5-dihydro-2,5-dioxo-
6-Maleimidocaproicacid
PubChem11039
(EMCA)
(EMCA);6-Maleimidocaproic acid
N-(6-oxo-

MDL Number

MFCD00043140

Customs Code

2925190090

FAQ

What is 6-Maleimidocaproic Acid (CAS: 55750-53-3)?

6-Maleimidocaproic Acid (CAS: 55750-53-3) is a synthetic organic compound with the chemical formula C7H12N2O2. It is a white crystalline solid with a carboxylic acid group and a maleimide functional group, making it reactive and suitable for chemical conjugation. This compound is commonly used in bioconjugation and peptide synthesis due to its unique reactivity and stability.

What are the main uses of 6-Maleimidocaproic Acid (CAS: 55750-53-3)?

6-Maleimidocaproic Acid (CAS: 55750-53-3) is widely utilized in pharmaceutical research for drug development and targeted therapies. It serves as a key reagent in industrial applications, including the production of polymers and coatings. In research, it is employed for molecular labeling and crosslinking. Its versatility also extends to biochemical assays and antibody conjugation.

Is 6-Maleimidocaproic Acid (CAS: 55750-53-3) safe?

6-Maleimidocaproic Acid (CAS: 55750-53-3) is generally considered safe when handled properly, but it requires caution due to potential skin and eye irritation. Safety data sheets (SDS) recommend wearing gloves, goggles, and a lab coat during handling. It is not classified as highly toxic, but inhalation and ingestion should be avoided. Proper ventilation and adherence to OSHA guidelines are essential for safe use.

How should 6-Maleimidocaproic Acid (CAS: 55750-53-3) be stored?

6-Maleimidocaproic Acid (CAS: 55750-53-3) should be stored in a sealed container at 2-8°C to maintain stability. It is sensitive to moisture and light, so storage in a cool, dry, and dark environment is critical. Avoid exposure to air to prevent oxidation. Keep away from incompatible substances and ensure proper labeling for safe handling and storage.