Bleomycin A5 Hydrochloride(1:x)

Basic Information

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CAS Number

55658-47-4

Molecular Formula

C57H90ClN19O21S2

Molecular Weight

1477 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCCNCCCCN)O.Cl

InChI

InChI=1S/C57H89N19O21S2.ClH/c1-22-35(73-48(76-46(22)61)27(14-33(60)80)68-15-26(59)47(62)86)52(90)75-37(43(28-16-65-21-69-28)95-56-45(41(84)39(82)31(17-77)94-56)96-55-42(85)44(97-57(63)92)40(83)32(18-78)93-55)53(91)70-24(3)38(81)23(2)49(87)74-36(25(4)79)51(89)67-13-8-34-71-30(20-98-34)54-72-29(19-99-54)50(88)66-12-7-11-64-10-6-5-9-58;/h16,19-21,23-27,31-32,36-45,55-56,64,68,77-79,81-85H,5-15,17-18,58-59H2,1-4H3,(H2,60,80)(H2,62,86)(H2,63,92)(H,65,69)(H,66,88)(H,67,89)(H,70,91)(H,74,87)(H,75,90)(H2,61,73,76);1H

InChIKey

NRVKJXFKQWUKCB-UHFFFAOYSA-N

LogP

-0.63200

Complexity

2620

Synonyms & References

English

BLEOCIN Antibiotic; Bleomycin A5 HCl
T2UC5J38DD
Bleomycinamide, N(sup 1)-(3-((4-aminobutyl)amino)propyl)-, hydrochloride
UNII-T2UC5J38DD
AS-77835
Bleomycin A5 HCl; Bleocin(tm), streptomyces verticillus
Pingyangmycin hydrochloride
Bleomycin A5 HCl
Bleomycin A5 hydrochloride
N1-[3-[(4-Aminobutyl)amino]propyl]bleomycinamide Hydrochloride
BCP12575
55658-47-4
CHEBI:201414
BLEOCIN(TM), STREPTOMYCES VERTICILLUS
N1-(3-((4-Aminobutyl)amino)propyl)bleomycinamide hydrochloride
Bleomycin A5 Hydrochloride Salt
Bleomycin A5 Hydrochloride
N1-[3-[(4-Aminobutyl)amino]propyl]bleomycinamide hydrochloride
Bleomycin A5 Hydrochlorid
BLEOCIN
BleoMycin A5 HCL
BLEOCIN(TM)
BLEOCIN(TM) ANTIBIOTIC
BleoMycin A5 Hydrochloride(PingyangMycin hydrochloride)
n(sup1)-(3-((4-aminobutyl)amino)propyl)bleomycinamidehydrochloride
n(sup1)-(3-((4-aminobutyl)amino)propyl)-bleomycinamidhydrochloride

MDL Number

MFCD01740724

FAQ

What is Bleomycin A5 Hydrochloride (CAS: 55658-47-4)?

Bleomycin A5 Hydrochloride (CAS: 55658-47-4) is an antitumor antibiotic derived from Streptomyces verticillus. It contains bleomycin A5 subunit conjugated with hydrochloride. This compound is used in the treatment of various types of cancer, particularly lung and testicular cancer.

What are the main uses of Bleomycin A5 Hydrochloride (CAS: 55658-47-4)?

Bleomycin A5 Hydrochloride (CAS: 55658-47-4) is primarily used as an antitumor agent in the treatment of cancers such as small cell lung cancer, testicular cancer, and head and neck cancer. It is also used in combination with other chemotherapy drugs to enhance therapeutic efficacy.

Is Bleomycin A5 Hydrochloride (CAS: 55658-47-4) safe?

Bleomycin A5 Hydrochloride (CAS: 55658-47-4) can be safe when used under medical supervision. However, it is associated with potential side effects such as lung fibrosis, hypersensitivity reactions, and nephrotoxicity. Proper dosing and monitoring are essential to ensure patient safety.

How should Bleomycin A5 Hydrochloride (CAS: 55658-47-4) be stored?

Bleomycin A5 Hydrochloride (CAS: 55658-47-4) should be stored in a tightly sealed container at room temperature (15°C to 25°C) to protect it from light. It should be kept away from moisture and direct sunlight to maintain its stability and potency.