2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine

Basic Information

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CAS Number

5466-43-3

Molecular Formula

C7H6Cl2N2

Molecular Weight

189.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

71-79 °C

Boiling Point

307 ºC

Flash Point

168 ºC

Refractive Index

1.583

SMILES

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C1CC2=C(C1)N=C(N=C2Cl)Cl

InChI

InChI=1S/C7H6Cl2N2/c8-6-4-2-1-3-5(4)10-7(9)11-6/h1-3H2

InChIKey

GDHHAOFBLGZCMI-UHFFFAOYSA-N

LogP

2.2721

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

153

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

5466-43-3
AKOS005208132
SCHEMBL633261
MFCD09750204
AM20100346
5H-Cyclopentapyrimidine, 2,4-dichloro-6,7-dihydro-
J-507148
GDHHAOFBLGZCMI-UHFFFAOYSA-N
2,4-dichloro-6,7-dihydro-5H-cyclopenta[d][1,3]chlorazine
NSC27369
FT-0682903
EN300-49946
F2108-0236
NSC-27369
CS-W008301
A852599
2,4-dichloro-6,7-dihydro-5h-cyclopenta[d]pyrimidine
2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine, 95%
Z596251606
2,4-DICHLORO-5,6-TRIMETHYLENEPYRIMIDINE
SY022226
DTXSID00282687
BCP29526
2,4-dichloro-5H,6H,7H-cyclopenta[d]pyrimidine
2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
AB51369
2,4-dichloro-6,7-dihydro-5h-cyclopenta[d]-pyrimidine
BF-0704
2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
2,4-DICHLORO-5,6,7,8-TETRAHYDROQUINAZOLINE
2,4-Dichloro-5H,6H,7H-cyclopenta[d]pyrimidine

MDL Number

MFCD09750204

FAQ

What are the physical and chemical properties of 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS: 5466-43-3)?

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine is a white crystalline solid with a molecular weight of approximately 199.02 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong bases and reducing agents. This compound is known for its low solubility in water and high stability under normal conditions.

How is 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS: 5466-43-3) typically synthesized?

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine can be synthesized via a multistep reaction starting from 2,4-dichloropyrimidine. The key steps involve the addition of a dihydrocyclopentyl ring via a Wittig reaction followed by a reduction to form the final product. This process typically requires careful control of temperature and reagents to achieve high yield and selectivity.

What industries use 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS: 5466-43-3)?

2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine is primarily used in the pharmaceutical industry for the synthesis of certain antiviral drugs. It is also utilized in the polymer industry as a precursor for synthesizing various polymer materials and in the semiconductor industry for specific applications in electronic device manufacturing.

What precautions should be taken when handling 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS: 5466-43-3)?

When handling 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up using appropriate protocols, and the substance should be stored in a cool, dry place away from incompatible materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.