Apremilast Impurity 26

Basic Information

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CAS Number

5434-20-8

Molecular Formula

C8H7NO4

Molecular Weight

181.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

180-185 °C

Boiling Point

436.4°C at 760 mmHg

Flash Point

217.7±27.3 °C

SMILES

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C1=CC(=C(C(=C1)N)C(=O)O)C(=O)O

InChI

InChI=1S/C8H7NO4/c9-5-3-1-2-4(7(10)11)6(5)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)

InChIKey

WGLQHUKCXBXUDV-UHFFFAOYSA-N

LogP

0.6652000000000002

Topological Polar Surface Area

100.62000000000002 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

228

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AC-6693
3-Aminophthalic acid
EINECS 226-595-9
A7900
Q-103169
3-Aminophthalicacid
5434-20-8
1,2-Benzenedicarboxylic acid, diisooctyl ester_Gurudeeban & Satyavani
EN300-173810
1,2-Benzenedicarboxylic acid, amino-
Phthalic acid, 3-amino-
NSC15741
o-Aminophthalic acid
AMY22072
UNII-7XV0V19ZDG
3-aminopthalic acid
FT-0613472
3-Amino-phthalic acid
DTXSID9063879
A854948
NS00033052
3-Amino-1,2-benzenedicarboxylic acid hydrochloride
3-Amino-1,2-benzenedicarboxylic acid
BDBM50493089
POMNLIDOMIDE METABOLITE M2
857040-74-5
J-511720
1,2-Benzenedicarboxylic acid, 3-amino-
AKOS004114683
MFCD00075053
7XV0V19ZDG

MDL Number

MFCD00075053

Customs Code

2922499990

FAQ

What is Apremilast Impurity 26 (CAS: 5434-20-8)?

Apremilast Impurity 26 (CAS: 5434-20-8) is a chemical compound identified as an impurity in the pharmaceutical drug Apremilast. It is typically a white to off-white solid with low solubility in water. The compound's exact chemical formula and molecular weight are not widely published, but it is structurally related to Apremilast, which has the formula C19H26N2O3S. Its presence is monitored during drug synthesis and quality control processes to ensure safety and efficacy.

What are the main uses of Apremilast Impurity 26 (CAS: 5434-20-8)?

Apremilast Impurity 26 (CAS: 5434-20-8) is primarily used in pharmaceutical research and quality control to identify and quantify impurities in Apremilast production. It may also serve as a reference standard for analytical testing in drug development. Its applications are limited to ensuring regulatory compliance and studying the stability of Apremilast in medicinal formulations.

Is Apremilast Impurity 26 (CAS: 5434-20-8) safe?

Safety data for Apremilast Impurity 26 (CAS: 5434-20-8) is limited, but as an impurity, it is generally considered less toxic than the parent compound Apremilast. Handling precautions include using appropriate personal protective equipment (PPE) and avoiding inhalation or skin contact. It should be stored securely and disposed of according to local regulations to meet safety standards in pharmaceutical settings.

How should Apremilast Impurity 26 (CAS: 5434-20-8) be stored?

Apremilast Impurity 26 (CAS: 5434-20-8) should be stored in a cool, dry place, away from direct light, and in a tightly sealed container to maintain stability. It is recommended to keep it at 2-8°C and protect it from moisture to prevent degradation. Proper storage ensures compliance with pharmaceutical standards and maintains the compound's integrity for analytical purposes.