2,4-Dimethyl-1,3-thiazole

Basic Information

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CAS Number

541-58-2

Molecular Formula

C5H7NS

Molecular Weight

113.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

No data available

Boiling Point

144-146 ºC (719 torr)

Water Solubility

Slightly soluble in water

Flash Point

42 ºC

Refractive Index

1.5081-1.5101

SMILES

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Cc1csc(C)n1

InChI

InChI=1S/C5H7NS/c1-4-3-7-5(2)6-4/h3H,1-2H3

InChIKey

OBSLLHNATPQFMJ-UHFFFAOYSA-N

LogP

1.75994

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

65.099

Safety Information

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GHS Hazard Pictograms

H226

H315

H319

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Sensitiveness

对湿度敏感

Synonyms & References

English

2,4-Dimethylthiazole
2,4-DIMETHYL-1,3-THIAZOLE
2,4-Dimethyl thiazole
Thiazole, 2,4-dimethyl-
2,4-Methylthiazole
2,4-dimethyl-thiazole
LHT97038OA
OBSLLHNATPQFMJ-UHFFFAOYSA-N
dimethylthiazol
NSC7510
zlchem 533
PubChem9937
2.4-dimethylthiazole
2,4 dimethylthiazole
Thiazole,4-dimethyl-
2, 4-Dimethylthiazole
KSC269I0D
WLN:
2,4-METHYLTHIAZOLE
2,4-DIMETHYLTHIAZOLE
2,4-dimethyl-thiazol
2 4-DIMETHYLTHIAZOLE 95+%
2,4-Dimethylthiazole,97%
dimethylthiazole,2,4-dimethylthiazole

MDL Number

MFCD00014509

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 2,4-Dimethyl-1,3-thiazole (CAS: 541-58-2)?

2,4-Dimethyl-1,3-thiazole is a crystalline solid with a molecular weight of approximately 128.18 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. This compound is moderately reactive, particularly with nucleophiles and electrophiles. It is commonly used in various chemical reactions due to its thiazole ring structure.

How is 2,4-Dimethyl-1,3-thiazole (CAS: 541-58-2) typically synthesized?

2,4-Dimethyl-1,3-thiazole is typically synthesized via the condensation of thiophenol and methyl acetoacetate under basic conditions. This reaction can be catalyzed by sodium hydroxide, and the yield is generally around 85%. The selectivity for the desired product is high, making this a reliable synthesis method.

What industries use 2,4-Dimethyl-1,3-thiazole (CAS: 541-58-2)?

2,4-Dimethyl-1,3-thiazole is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis. It is also utilized in the polymers industry for the production of certain specialty polymers. Additionally, it finds applications in sensors, particularly gas sensors, and in the semiconductor industry for electronic materials.

What precautions should be taken when handling 2,4-Dimethyl-1,3-thiazole (CAS: 541-58-2)?

When handling 2,4-Dimethyl-1,3-thiazole, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. It should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always consult the Safety Data Sheet (SDS) for detailed information on storage, handling, and disposal procedures.