4,5-Dichloro-1,2-Benzenediamine

Basic Information

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CAS Number

5348-42-5

Molecular Formula

C6H6Cl2N2

Molecular Weight

177.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

158-164 °C

Boiling Point

346.3°C at 760 mmHg

Water Solubility

Soluble in methanol and Dimethyl sulfoxide. Insoluble in water.

Flash Point

163.3 °C

Refractive Index

1.6400 (estimate)

SMILES

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C1=C(C(=CC(=C1Cl)Cl)N)N

InChI

InChI=1S/C6H6Cl2N2/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,9-10H2

InChIKey

IWFHBRFJOHTIPU-UHFFFAOYSA-N

LogP

2.1578

Topological Polar Surface Area

52.04 Å²

Hydrogen Bond Donor/Acceptor

4 / 2

Complexity

106

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

AC-22897
FT-0617153
4,5-Dichloro-phenylenediamine
4,5-Dichloro-ortho-phenylenediamine
4,5-Dichlorophenylene diamine
4,5-dichloro-1,2-phenylendiamine
NS00032769
2LUD2S3RUC
1,2-Benzenediamine, 4,5-dichloro-
DICHLORO-O-PHENYLENEDIAMINE, 4,5-
4,5-dichlorophenylenediamine
D2307
5348-42-5
4,5-dichlorophenylendiamine
NSC 1577
4,5-Dichloro-o-phenylenediamine, 97%
UNII-2LUD2S3RUC
A23848
EINECS 226-305-0
MFCD00007723
CCG-206428
4,5-Dichloro-1,2-benzenediamine
2-amino-4,5-dichloroaniline
4,5-dichloro-1,2-diaminobenzene
STR01907
4,5-dichlorobenzene-1,2-diamine
DTXSID70201663
EN300-21660
InChI=1/C6H6Cl2N2/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,9-10H
1,2-dichloro-4,5-phenylenediamine
o-Phenylenediamine,5-dichloro-

MDL Number

MFCD00007723

Customs Code

2921590090

FAQ

What regulatory guidelines apply to 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5)?

4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5) is subject to various regulatory guidelines. It falls under the criteria of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which requires specific hazard communication elements such as labels and safety data sheets. Additionally, under REACH regulations, manufacturers and importers must register the substance if it is produced or imported in quantities exceeding one tonne per year. The FDA and EPA may also require registration and reporting under specific circumstances. Compliance with these regulations is essential for safe handling and distribution.

Are there alternatives to 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5) in synthesis?

There are alternative reagents and compounds that can be used instead of 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5) in synthesis. Some common substitutes include 4-Aminobenzenesulfonic acid, 2-Chloro-4-nitroaniline, and 4-Chloro-1,2-benzenediamine. These alternatives may offer similar chemical properties but with different toxicity profiles and handling requirements, making them suitable for specific applications where 4,5-Dichloro-1,2-Benzenediamine may pose risks or regulatory challenges.

What is the market or research trend for 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5)?

The market for 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5) is currently stable with steady demand, particularly in the pharmaceutical and dye industries. Research trends indicate an increasing focus on the compound's use in developing novel drug candidates and pigments. However, due to its hazardous nature, there is a growing interest in safer alternatives and more sustainable manufacturing processes. Eco-friendly and less toxic chemical pathways are emerging as key areas of focus in research.

How should waste containing 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5) be handled?

Handling waste containing 4,5-Dichloro-1,2-Benzenediamine (CAS: 5348-42-5) requires careful consideration due to its hazardous properties. Waste should be collected in appropriate containers and stored under controlled conditions to prevent environmental contamination. Professional waste disposal services should be utilized to ensure proper incineration or chemical treatment. Environmental protection measures include ensuring no spillage during handling and the use of personal protective equipment. Compliance with local waste management regulations is crucial to avoid legal and environmental issues.