3-(Difluoromethoxy)-4-hydroxybenzaldehyde

Basic Information

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CAS Number

53173-70-9

Molecular Formula

C8H6F2O3

Molecular Weight

188.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

276.2±35.0°C at 760 mmHg

SMILES

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C1=CC(=C(C=C1C=O)OC(F)F)O

InChI

InChI=1S/C8H6F2O3/c9-8(10)13-7-3-5(4-11)1-2-6(7)12/h1-4,8,12H

InChIKey

BQWJKJOZIXNRID-UHFFFAOYSA-N

LogP

1.8060999999999998

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

175

Safety Information

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Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H412 Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

3-(Difluoromethoxy)-4-hydroxybenzaldehyde
3-Difluoromethoxy-4-hydroxybenzaldehyde
3-Difluoromethoxy-4-hydroxybenzaldehyd
QC-1128
AK142202
FCH1995381
AX8282077
AB0095011
DS-7499
SCHEMBL7372901
53173-70-9
DTXSID30611128
W17194
SY115747
A870801
AKOS003619367
BQWJKJOZIXNRID-UHFFFAOYSA-N
AC-27271
CS-W021772
MFCD00720656
DB-348141

MDL Number

MFCD00720656

FAQ

What are the physical and chemical properties of 3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9)?

3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9) is a crystalline compound with a molecular weight of approximately 211.08 g/mol. It has a melting point of 78-80°C and is slightly soluble in water. Chemically, it is reactive towards nucleophiles and can undergo electrophilic aromatic substitution reactions. The compound is also susceptible to hydrolysis under basic conditions.

How is 3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9) typically synthesized?

3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9) can be synthesized via the condensation of 4-hydroxybenzaldehyde with difluoromethanol in the presence of an acid catalyst. The reaction typically proceeds with high yield and good selectivity. The synthesis involves careful control of reaction conditions to ensure the desired product is formed.

What industries use 3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9)?

3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of polymers and as a precursor in sensor technology and semiconductor manufacturing due to its chemical reactivity.

What precautions should be taken when handling 3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9)?

Proper handling of 3-(Difluoromethoxy)-4-hydroxybenzaldehyde (CAS: 53173-70-9) requires the use of personal protective equipment (PPE), such as gloves and goggles. It should be handled in a well-ventilated area or under a fume hood. Spills should be cleaned up carefully using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.