Trimethylsilylpropargyl Alcohol

Basic Information

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CAS Number

5272-36-6

Molecular Formula

C6H12OSi

Molecular Weight

88.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Physical Properties

Boiling Point

76 °C/11 mmHg

Water Solubility

Not miscible with water.

Refractive Index

n20/D 1.451(lit.)

SMILES

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C[Si](C)(C)C#CCO

InChI

InChI=1S/C4H12Si/c1-5(2,3)4/h1-4H3

InChIKey

CZDYPVPMEAXLPK-UHFFFAOYSA-N

LogP

1.9544

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

120

Safety Information

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GHS Hazard Pictograms

H301

H315

H319

H335

H227

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H227 Combustible liquid
Flammable liquids

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Moisture Sensitive

Synonyms & References

English

3-(Trimethylsilyl)propargyl alcohol, 99%
3-(Trimethylsilyl)-2-propyn-1-ol
NSC-617397
5272-36-6
3-Trimethylsilylpropargylalcohol
3-Trimethylsilylpropargyl alcohol
A829227
J-802120
MFCD00002913
SY020094
NS00044820
EN300-129296
1-Trimethylsilylpropargyl alcohol
3-(Trimethylsilyl)-2-propyn-1-ol #
2-Propyn-1-ol, 3-(trimethylsilyl)-
3-Trimethylsilyl-2-propyn-1-ol
DS-14632
AKOS015950997
3-trimethylsilanyl-prop-2-yn-1-ol
3-(Trimethylsilyl)propargylalcohol
s20100
EINECS 226-094-5
DTXSID8063751
FT-0601962
CS-0173149
3-trimethylsilylprop-2-yn-1-ol
NSC617397
T1500
3-(Trimethylsilyl)propargyl alcohol;3-(Trimethylsilyl)prop-2-yn-1-ol
CS-W007721
J-802302

MDL Number

MFCD00002913

Customs Code

2931900090

FAQ

What is Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6)?

Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6) is a colorless liquid with a molecular structure characterized by a propargyl alcohol moiety attached to a trimethylsilyl group. It is widely used in synthetic chemistry and pharmaceuticals for its reactivity and stability.

What are the main uses of Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6)?

Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6) is primarily used in organic synthesis, particularly for protecting groups and in the preparation of functionalized compounds. It is also utilized in the pharmaceutical and agrochemical industries for the synthesis of drug candidates and crop protection agents.

Is Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6) safe?

Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6) is generally considered safe for laboratory use with proper handling. However, it should be handled with caution as it is flammable and may irritate the skin and eyes. Protective measures include the use of gloves, goggles, and appropriate ventilation.

How should Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6) be stored?

Trimethylsilylpropargyl Alcohol (CAS: 5272-36-6) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a sealed container to prevent evaporation and contamination. Avoid storing it near incompatible chemicals such as strong oxidizers or acids.