Giemsa stain | CAS No. 51811-82-6

Giemsa stain

Basic Information

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CAS Number

51811-82-6

Molecular Formula

C14H14ClN3S

Molecular Weight

291.8 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

300 °C

Water Solubility

Insoluble in water (<0.1%), methanol (5.8 mg/L), and ethanol.

Solubility

ethanol: 1 mg/mL

SMILES

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C[N+](=C1C=CC2=NC3=C(C=C(C=C3)N)SC2=C1)C.[Cl-]

InChI

InChI=1S/C14H13N3S.ClH/c1-17(2)10-4-6-12-14(8-10)18-13-7-9(15)3-5-11(13)16-12;/h3-8,15H,1-2H3;1H

InChIKey

NALREUIWICQLPS-UHFFFAOYSA-N

LogP

0.96400

Complexity

483

Safety Information

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GHS Hazard Pictograms

H301

H311

H318

H331

H370

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H318 Causes serious eye damage
Serious eye damage/eye irritation

H331 Toxic if inhaled
Acute toxicity, inhalation

H370 Causes damage to organs
Specific target organ toxicity, single exposure

Sensitiveness

对湿度敏感

Synonyms & References

English

EINECS 208-510-7
NSC 374111
Giemsa's stain
Fast Giemsa Stain Kit
n-(7-amino-3h-phenothiazin-3-ylidene)-n-methylmethanaminium chloride
NSC-326661
N,N-Dimethylthionine
EINECS 263-491-2
CS-0022121
CHEBI:87637
METHYLTHIONINIUM CHLORIDE HYDRATE IMPURITY B [EP IMPURITY]
AZURE A CARBACRYLIC RESIN
Methylene Azure A
MS-24168
Azure A chloride, certified by the Biological Stain Commission, Dye content 70 %
Azure A chloride, certified by the Biological Stain Commission
BDBM50055937
Azure A chloride, Dye content >=70 %
Mancha Giemsa
62298-43-5
F72133
AMY22390
giemsa-stain
MFCD00012112
Dimethylthionine
CCRIS 9315
FT-0622538
DTXSID2040157
C.I. 52005
EINECS 257-438-2
A901233

MDL Number

MFCD00081642

Customs Code

32129000

FAQ

What is Giemsa stain (CAS: 51811-82-6)?

Giemsa stain, with CAS number 51811-82-6, is a synthetic dye commonly used in cytology and histology. It is a mixture of methylene blue and eosin, primarily used for staining cells and tissues to enhance contrast under a microscope. Its chemical composition includes triphenylmethane and acidic dyes, making it effective for differentiating between various cellular components.

What are the main uses of Giemsa stain (CAS: 51811-82-6)?

Giemsa stain is widely used in medical diagnostics, particularly for staining blood and bone marrow samples to identify parasites, bacteria, and other microorganisms. It is also employed in research for visualizing chromosomes and in industrial applications for quality control in biological materials. Its versatility makes it a key tool in microbiology and pathology.

Is Giemsa stain (CAS: 51811-82-6) safe?

Giemsa stain is generally considered safe when used according to established protocols, but it contains potential irritants and should be handled with care. Safety guidelines recommend using protective gloves, goggles, and ensuring proper ventilation. It is classified as a low-toxicity dye, but adherence to safety standards is crucial to minimize exposure risks.

How should Giemsa stain (CAS: 51811-82-6) be stored?

Giemsa stain should be stored in a cool, dark place away from direct sunlight to maintain its stability and effectiveness. It is typically kept in airtight containers at temperatures below 25°C and humidity levels below 60%. Proper storage is essential to prevent degradation and ensure long-term usability.