5-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone hydrochloride (1:1)

Basic Information

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CAS Number

51781-21-6

Molecular Formula

C16H25ClN2O3

Molecular Weight

328.84 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

278 ºC

SMILES

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CC(C)(C)NCC(COC1=CC=CC2=C1CCC(=O)N2)O.Cl

InChI

InChI=1S/C16H24N2O3.ClH/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13;/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20);1H

InChIKey

FYBXRCFPOTXTJF-UHFFFAOYSA-N

LogP

2.1209000000000002

Topological Polar Surface Area

70.59 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

354

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 in male mice, rats (mg/kg): 810, 1380 orally; 54.5, 158 i.v.; 380, 400 i.p. (Lang)

Synonyms & References

English

SW197155-3
5-(3-((tert-Butyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2-quinolone monohydrochloride
AKOS027379166
EX-A1257
2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro, monohydrochloride
5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-2(1H)-quinolinone Hydrochloride
Carteolol Monohydrochloride
CARTEOLOL HYDROCHLORIDE [USP-RS]
4797W6I0T4
s4278
5-(3-t-butylamino-2-hydroxypropoxy)-3,4-dihydrocarbostyril hydrochloride
Carteolol Hydrochloride ,(S)
NSC-760060
Carteolol-d9Hydrochloride
CARTEOLOL HYDROCHLORIDE [USAN]
Hydrochloride, Carteolol
Ocupress
Abbott 43326
NSC760060
OPC 1085
Tox21_110654
CARTEOLOL HYDROCHLORIDE (USP IMPURITY)
Endak
DTXCID2025478
5-(3-tert-Butylamino-2-hydroxy-propoxy)-3,4-dihydro-2(1H)-chinolinon-hydrochlorid
HY-17495A
WLN: T66 BMVT&J GO1YQ1MX1&1&1 &GH
5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydroquinolin-2(1H)-one hydrochloride
5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydrocarbostyril monohydrochloride
NS00089033
Pharmakon1600-01505519

MDL Number

MFCD00941499

FAQ

What regulatory guidelines apply to 5-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone hydrochloride (CAS: 51781-21-6)?

The compound must comply with GHS classification, REACH regulations, and FDA/EPA requirements. It is classified as a hazardous substance according to the GHS, and may require registration under REACH. Specific handling and storage instructions are outlined in the SDS (Safety Data Sheet).

Are there alternatives to 5-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone hydrochloride (CAS: 51781-21-6) in synthesis?

Synthesis alternatives may include similar quinoline derivatives or other aromatic compounds with similar functional groups. Common substitutes might involve using different amino or alkoxy groups. It is recommended to consult literature or databases for specific analogs and isomers.

What is the market or research trend for 5-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone hydrochloride (CAS: 51781-21-6)?

Market trends suggest increasing research interest in this compound due to its pharmacological properties. It is particularly explored in the field of medicinal chemistry for potential drug development. Price trends are influenced by supply and demand, with demand driven by pharmaceutical and academic research.

How should waste containing 5-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-3,4-dihydro-2(1H)-quinolinone hydrochloride (CAS: 51781-21-6) be handled?

Waste should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration or safe landfilling should be conducted under controlled conditions to prevent environmental contamination. Always refer to local regulations and follow waste management protocols to ensure compliance with environmental protection laws.