1-(2,4-Dichlorobenzyl)piperazine

Basic Information

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CAS Number

51619-56-8

Molecular Formula

C11H14Cl2N2

Molecular Weight

245.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

Boiling Point

116-118/0.08mm

Refractive Index

n20/D 1.571

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

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C1CN(CCN1)CC2=C(C=C(C=C2)Cl)Cl

InChI

InChI=1S/C11H14Cl2N2/c12-10-2-1-9(11(13)7-10)8-15-5-3-14-4-6-15/h1-2,7,14H,3-6,8H2

InChIKey

VYKXBWXIOSLDQR-UHFFFAOYSA-N

LogP

2.66530

Complexity

195

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SCHEMBL593572
AS-11227
1-[(2,4-dichlorophenyl)methyl]piperazine
VYKXBWXIOSLDQR-UHFFFAOYSA-N
1-(2,4-Dichloro-benzyl)-piperazine
51619-56-8
1-(2,4-Dichlorobenzyl)piperazine
4-Ethoxylphenyl-4-Trans-Propylcyclohexylbenzoate
EN300-651532
GS1990
A924276
FT-0689865
1-(2,4-Dichlorobenzyl)piperazine, 97%
DTXSID00328519
CS-0453176
AKOS000125691
FT-0689864
BB 0249403
MFCD03407487
1-(2,4-dichlorobenzyl)piperazine dihydrochloride
Piperazine,1-[(2,4-dichlorophenyl)methyl]-
[(2,4-dichlorophenyl)methyl]piperazine
1-(2,4-dichlorobenzyl)-piperazine
1-(2,4-dichloro-benzyl)-piperazine
657840_ALDRICH
AC1L90QI
ACMC-1AQ02
AG-F-74957
SureCN593572

MDL Number

MFCD03407487

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8)?

1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8) is a crystalline solid with a molecular weight of approximately 247.03 g/mol. It has a low water solubility and is relatively stable under normal conditions. The compound is known for its reactivity with electrophiles and can undergo substitution reactions under specific conditions.

How is 1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8) typically synthesized?

1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8) is usually synthesized via nucleophilic substitution reactions, where a piperazine anion reacts with 2,4-dichlorobenzyl halide. Commonly, this reaction is catalyzed by a base such as potassium carbonate or sodium hydroxide, and the yield is typically around 70-80% with good selectivity.

What industries use 1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8)?

1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8) is primarily used in pharmaceutical applications, particularly in the development of certain types of antipsychotic drugs. It also finds applications in the synthesis of polymers and as a precursor in the production of other organic compounds.

What precautions should be taken when handling 1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8)?

When handling 1-(2,4-Dichlorobenzyl)piperazine (CAS: 51619-56-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for comprehensive safety information.