(R)-(3-trifluoromethyl)mandelic acid | CAS No. 51359-73-0

(R)-(3-trifluoromethyl)mandelic acid

Basic Information

CAS Number

51359-73-0

Molecular Formula

C9H7F3O3

Molecular Weight

220.15 g/mol

AD

Basic Physical Properties

Physical State

White to Yellow Solid

C1=CC(=CC(=C1)C(F)(F)F)C(C(=O)O)O

InChI

InChI=1S/C9H7F3O3/c10-9(11,12)6-3-1-2-5(4-6)7(13)8(14)15/h1-4,7,13H,(H,14,15)/t7-/m1/s1

InChIKey

WECBNRQPNXNRSJ-SSDOTTSWSA-N

LogP

1.8234000000000001

Topological Polar Surface Area

57.53 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

239

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • (R)-(3-TRIFLUOROMETHYL)MANDELIC ACID
  • (R)-2-hydroxy-2-(3-(trifluoromethyl)phenyl)acetic acid
  • (R)-HYDROXY-(3-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID
  • AC1OGOZ2
  • ACT09801
  • AG-F-73720
  • CTK8F2019
  • SureCN5159944
  • (r)-3-trifluoromethylmandelic acid
  • (2R)-2-hydroxy-2-[3-(trifluoromethyl)phenyl]acetic acid
  • 51359-73-0
  • (R)-2-Hydroxy-2-(3-(trifluoromethyl)phenyl)aceticacid
  • WECBNRQPNXNRSJ-SSDOTTSWSA-N
  • EN300-4406848
  • DTXSID40428249
  • CS-0171098
  • (R)-(3-trifluoromethyl)mandelic acid
  • MFCD09991747
  • AS-38553
  • SCHEMBL5159944
  • AKOS027327701
  • A913188

MDL Number

MFCD09991747

FAQ

What regulatory guidelines apply to (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0)?

The (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0) must adhere to GHS (Globally Harmonized System of Classification and Labeling of Chemicals) guidelines for classification and labeling. It also falls under REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) regulations in the EU, where manufacturers and importers need to register the substance if the annual tonnage exceeds one ton. Additionally, FDA and EPA guidelines apply for the use of this chemical in the United States, ensuring safety and compliance with environmental and health standards.

Are there alternatives to (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0) in synthesis?

Alternatives to (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0) include its enantiomer (S)-(3-trifluoromethyl)mandelic acid, as well as isomers such as (R)-(2-trifluoromethyl)mandelic acid. Other common substitutes include related compounds like trifluoromethylbenzoic acid and trifluoromethyl salicylic acid. These alternatives offer similar functionalities and can be used in various synthetic pathways, depending on the specific requirements of the synthesis process.

What is the market or research trend for (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0)?

The market for (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0) is currently growing due to its applications in pharmaceuticals and agrochemicals. Research trends focus on its use as a chiral building block in asymmetric synthesis and as a precursor in the development of new drugs. Market trends show increasing demand for this compound, driven by advancements in synthetic chemistry and pharmaceutical research. However, price fluctuations can impact the market dynamics, with ongoing research aimed at improving production methods and reducing costs.

How should waste containing (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0) be handled?

Waste containing (R)-(3-trifluoromethyl)mandelic acid (CAS: 51359-73-0) should be carefully managed to ensure environmental safety. Collect waste in appropriate containers and label them appropriately. Incineration is a common method for disposal, but it should be conducted in a professional incineration facility. Alternatively, professional waste disposal services can handle bulk waste. Environmental protection measures include proper ventilation and personal protective equipment to prevent exposure. Always follow local and regional regulations for hazardous waste disposal.

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