2-(2-Methoxy-5-nitrophenyl)acetic acid

Basic Information

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CAS Number

51073-04-2

Molecular Formula

C9H9NO5

Molecular Weight

211.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

153-155℃

SMILES

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COC1=C(C=C(C=C1)[N+](=O)[O-])CC(=O)O

InChI

InChI=1S/C9H9NO5/c1-15-8-3-2-7(10(13)14)4-6(8)5-9(11)12/h2-4H,5H2,1H3,(H,11,12)

InChIKey

TZQZNDOEOCOJFS-UHFFFAOYSA-N

LogP

1.75370

Complexity

249

Synonyms & References

English

2-(2-Methoxy-5-nitrophenyl)acetic acid
(2-Methoxy-5-nitrophenyl)acetic acid
(2-methoxy-5-nitro-phenyl)-acetic acid
<2-Methoxy-5-nitro-phenyl>-essigsaeure
F9995-0232
EN300-236274
51073-04-2
2-methoxy-5-nitrophenylacetic acid
STL282259
J-509835
CS-0072069
DTXSID70393254
D95603
2-METHOXY-5-NITRO BENZENE ACETIC ACID 99+% HPLC
2-(2-methoxy-5-nitrophenyl)acetic acid
AKOS000112341
AS-67583
AMY821
DB-329168
2-(2-methoxy-5-nitrophenyl)aceticacid
SCHEMBL4364148

MDL Number

MFCD02664832

Customs Code

2918990090

FAQ

What are the physical and chemical properties of 2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2)?

2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2) is a crystalline solid with a molecular weight of approximately 246.13 g/mol. It has a moderate solubility in water and is slightly soluble in common organic solvents. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is a weak acid due to the presence of the carboxylic acid group.

How is 2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2) typically synthesized?

2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2) can be synthesized through a multi-step process involving the nitration of a methylated phenol followed by acetylation. Commonly, this involves the use of nitric acid and sulfuric acid as nitrating agents, and acetic anhydride as the acetylating agent. The process requires careful temperature control and the use of appropriate catalysts to ensure high selectivity and yield.

What industries use 2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2)?

2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2) is used in various industries, particularly in pharmaceuticals for the synthesis of certain drugs. It is also utilized in the polymer industry as a monomer or intermediate. Additionally, it has applications in the production of sensors and semiconductors, where its specific functional groups make it suitable for various chemical reactions.

What precautions should be taken when handling 2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2)?

When handling 2-(2-Methoxy-5-nitrophenyl)acetic acid (CAS: 51073-04-2), it is crucial to use appropriate personal protective equipment (PPE), including gloves and goggles. This compound should be stored in a cool, dry place away from direct sunlight and sources of heat. It should be used in a well-ventilated area or under a fume hood to avoid inhalation of dust or vapors. In case of a spill, it is important to follow the safety data sheet (SDS) guidelines for proper cleanup and disposal.