1,2-Dimethoxy-4-methylbenzene

Basic Information

View in Editor

CAS Number

494-99-5

Molecular Formula

C9H12O2

Molecular Weight

152.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

22-23 °C

Boiling Point

133-135 °C/50 mmHg

Refractive Index

n20/D 1.528(lit.)

SMILES

View in Editor

COc1ccc(C)cc1OC

InChI

InChI=1S/C9H12O2/c1-7-4-5-8(10-2)9(6-7)11-3/h4-6H,1-3H3

InChIKey

GYPMBQZAVBFUIZ-UHFFFAOYSA-N

LogP

2.01222

Topological Polar Surface Area

18.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

114

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1,2-Dimethoxy-4-methylbenzene
3,4-Dimethoxytoluene
3,4-Dimethoxytoluene
4-Methylveratrole
Benzene,1,2-dimethoxy-4-methyl
Homoveratrole
Benzene, 1,2-dimethoxy-4-methyl-
4-Methylveratrol
4-Methyl-1,2-dimethoxybenzene
1,2-Dimethoxy-4-methyl-benzene
349X0G2SSF
GYPMBQZAVBFUIZ-UHFFFAOYSA-N
homoveratrol
4 -methylveratrole
3.4-dimethoxytoluene
Toluene,4-dimethoxy-
Veratrole, 4-methyl-
PubChem23595
3,4-dimethoxy-toluene
Toluene, 3,4-dimethoxy-
KS

MDL Number

MFCD00016651

Customs Code

29093090

FAQ

What are the physical and chemical properties of 1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5)?

1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5) is a clear, colorless liquid with a molecular weight of approximately 180.22 g/mol. It has a moderately high boiling point of 277°C and a low melting point of -25°C. The compound is moderately soluble in water but soluble in organic solvents. It is moderately reactive under basic conditions and less reactive under acidic conditions. It is stable under normal storage conditions but should be kept away from strong oxidizing agents and heat sources.

How is 1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5) typically synthesized?

1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5) can be synthesized via the Friedel-Crafts alkylation of methylbenzene with methanol in the presence of an acid catalyst, such as aluminum chloride. The reaction typically yields a product with high selectivity and good yield. Proper handling of the reactants and the use of appropriate safety measures are essential during the synthesis process.

What industries use 1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5)?

1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of organic materials, such as polymers and sensors, due to its unique chemical properties. Additionally, it has applications in the semiconductor industry as an intermediate in the manufacturing of electronic materials.

What precautions should be taken when handling 1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5)?

When handling 1,2-Dimethoxy-4-methylbenzene (CAS: 494-99-5), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Avoid contact with skin and eyes. In case of a spill, use appropriate spill control materials and follow standard safety procedures. Always consult the safety data sheet (SDS) for detailed information on handling and storage.