3-[(2S)-2-Piperidinyl]pyridine

Basic Information

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CAS Number

494-52-0

Molecular Formula

C10H14N2

Molecular Weight

162.24 g/mol

EINECS

207-791-3

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

9°C

Boiling Point

270-272°C

Density

1,0455 g/cm3

Flash Point

93°C

Solubility

DMSO : 100 mg/mL (616.41 mM)

Refractive Index

1.5430

Specific Rotation

D20 -83.1°

SMILES

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C1CCNC(C1)C2=CN=CC=C2

InChI

InChI=1S/C10H14N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8,10,12H,1-2,5,7H2/t10-/m0/s1

InChIKey

MTXSIJUGVMTTMU-JTQLQIEISA-N

LogP

1.8961999999999999

pKa

8.98±0.10(Predicted)

Topological Polar Surface Area

24.92 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

136

Safety Information

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Hazard Class

Class 6.1 Class 6.1

Toxicity

LDLo orl-dog: 50 mg/kg JPETAB 48,95,33

Synonyms & References

English

HSDB 3462
NSC87504
CAS-494-52-0
Pyridine, 3-(2-pyridyl) piperidine
NICOTINE IMPURITY G [EP IMPURITY]
WLN: T6NJ C- BT6MTJ
NICOTINE RESINATE IMPURITY G (EP IMPURITY)
NICOTINE IMPURITY G (EP IMPURITY)
Anabasine
3-((2S)-piperidin-2-yl)pyridine
3-(2S)-2-Piperidinylpyridine
1ST165999
MLS000737148
Anabasin
AKOS000277110
CHEBI:74
BRN 0082637
2-(3'-Pyridyl) piperidine
(S)-anabasine
Piperidine, 2-(3-pyridyl)-
ANABASINE [HSDB]
CS-0013343
L-(-)-Anabasine
(S)-Snabasine
(S)-3-(piperidin-2-yl)=pyridine
Anabazin
(S)-3-(Piperidin-2-yl)pyridine
(-)-Anabasine
CHEMBL1526229
NICOTINE RESINATE IMPURITY G [EP IMPURITY]
DTXCID7021607

MDL Number

MFCD00871391

EC Number

207-791-3

Customs Code

29333990

FAQ

What regulatory guidelines apply to 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0)?

3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and the REACH regulations. In the USA, it is also subject to FDA and EPA requirements. Manufacturers and distributors must ensure compliance with these guidelines to ensure safe handling, storage, transportation, and disposal.

Are there alternatives to 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0) in synthesis?

Several alternatives can be used in the synthesis of 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0), such as 3-[(2R)-2-Piperidinyl]pyridine and 3-[(2S)-2-Methylpiperidinyl]pyridine. Additionally, alternative reagents like pyridine derivatives with different functional groups can be explored depending on the specific reaction conditions.

What is the market or research trend for 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0)?

The market for 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0) is growing due to its applications in pharmaceuticals and agrochemicals. Research trends are focusing on its potential as an intermediate for synthesizing bioactive compounds, with increasing emphasis on sustainable and eco-friendly production methods.

How should waste containing 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0) be handled?

Waste containing 3-[(2S)-2-Piperidinyl]pyridine (CAS: 494-52-0) should be collected in appropriate containers and labeled as hazardous. It should be disposed of through professional waste disposal services that comply with local regulations. Environmental protection precautions include proper incineration or chemical treatment to neutralize the compound before disposal.