Atropic acid | CAS No. 492-38-6

Atropic acid

Basic Information

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CAS Number

492-38-6

Molecular Formula

C9H8O2

Molecular Weight

148.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

105.0 to 109.0 deg-C

Boiling Point

267°C

Flash Point

174.521°C

Refractive Index

1.5049 (estimate)

SMILES

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C=C(C1=CC=CC=C1)C(=O)O

InChI

InChI=1S/C9H8O2/c1-7(9(10)11)8-5-3-2-4-6-8/h2-6H,1H2,(H,10,11)

InChIKey

ONPJWQSDZCGSQM-UHFFFAOYSA-N

LogP

1.7844

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

166

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

atropasaure
alpha-Toluic acid, alpha-methylene-
Benzeneacetic acid, .alpha.-methylene-
2-phenyl-acrylic acid
Z1201618094
DTXSID3075418
2-phenylprop-2-enoic acid
AKOS006345201
.alpha.-Phenylacrylic acid
SY051220
W-106030
NSC20987
Atropic acid
Benzeneacetic acid, alpha-methylene-
2-Propenoic acid, 2-phenyl-
NSC-20987
EN300-93624
UNII-TW16UA35S0
Ipratropium Bromide Impurity D
PS-3677
Q27290450
Ipratropium Bromide Imp. D (EP); 2-Phenylpropenoic Acid; Atropic Acid; Ipratropium Bromide Impurity D; Ipratropium Impurity D
2-Phenyl Acrylic Acid
AMY39233
Acrylic acid, 2-phenyl-
EINECS 207-753-6
492-38-6
2-Phenylacrylic acid
.ALPHA.-METHYLENEBENZENEACETIC ACID
NSC 20987
MFCD00046531

MDL Number

MFCD00046531

Customs Code

2916399090

FAQ

What are the physical and chemical properties of Atropic acid (CAS: 492-38-6)?

Atropic acid (CAS: 492-38-6) is a white to off-white crystalline solid with a molecular weight of 144.11 g/mol. It is slightly soluble in water but readily soluble in alcohol. Atropic acid is known for its acidity and can react with bases to form salts. It is stable under normal conditions but may decompose at high temperatures.

How is Atropic acid (CAS: 492-38-6) typically synthesized?

Atropic acid (CAS: 492-38-6) can be synthesized through the hydrolysis of atropine or scopolamine. Common methods include the use of strong acids like hydrochloric acid or sulfuric acid. The reaction is typically carried out in a one-pot process with good yield and selectivity.

What industries use Atropic acid (CAS: 492-38-6)?

Atropic acid (CAS: 492-38-6) is primarily used in the pharmaceutical industry as a building block for the synthesis of various alkaloids and as a precursor for the production of atropine and scopolamine. It also finds applications in the polymer industry for the synthesis of certain polymers with unique properties.

What precautions should be taken when handling Atropic acid (CAS: 492-38-6)?

When handling Atropic acid (CAS: 492-38-6), gloves, goggles, and a lab coat should be worn to protect against skin contact and eye irritation. This compound should be stored in a cool, dry place away from direct sunlight. In case of spills, it should be cleaned up immediately with appropriate chemical spill kits. Always refer to the Safety Data Sheet (SDS) for detailed safety information.