(8alpha,9R)-10,11-Dihydrocinchonan-9-ol

Basic Information

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CAS Number

485-64-3

Molecular Formula

C19H24N2O

Molecular Weight

296.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

230°

Boiling Point

438°C (rough estimate)

Refractive Index

1.5600 (estimate)

Specific Rotation

D15 -98° (alcohol)

SMILES

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CCC1CN2CCC1CC2C(C3=CC=NC4=CC=CC=C34)O

InChI

InChI=1S/C19H24N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h3-7,9,13-14,18-19,22H,2,8,10-12H2,1H3/t13-,14-,18-,19+/m0/s1

InChIKey

WFJNHVWTKZUUTR-KODHJQJWSA-N

LogP

3.388600000000002

Topological Polar Surface Area

36.36 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

388

Synonyms & References

English

DTXSID001315486
Q27269695
GNF-Pf-1324
(8.ALPHA.,9R)-10,11-DIHYDROCINCHONAN-9-OL
E78977
NS00079441
485-64-3
HYDROCINCHONIDINE [MI]
WFJNHVWTKZUUTR-KODHJQJWSA-N
(8
(3R,8S,9R)-10,11-Dihydrocinchonidine
EINECS 207-620-2
(8alpha,9R)-10,11-Dihydrocinchonan-9-ol
(-)-dihydrocinchonidine
SCHEMBL2404224
A,9R)-10,11-dihydro-Cinchonan-9-ol
CS-0091382
dihydrocinchonidine
8635CEW7CR
H1702
Cinchamidine
Hydrocinchonidine
CHEMBL585986
UNII-8635CEW7CR
(R)-((1S,2S,4S,5R)-5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanol
Cinchonan-9-ol,10,11-dihydro-, (8a,9R)-
DIHYDROCINCHONIDINE
(-)-CINCHONIDINE
(-)-hydrocinchonidine
(+)-cinchonine
10,11-dihydrocinchonidine

MDL Number

MFCD30489122

FAQ

What regulatory guidelines apply to (8alpha,9R)-10,11-Dihydrocinchonan-9-ol (CAS: 485-64-3)?

This compound must comply with the GHS classification, which categorizes it based on its physical and chemical properties. In the European Union, it is regulated under REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) for its manufacture, import, and use. For the United States, the FDA and EPA have specific requirements for its handling, storage, and disposal due to its potential environmental and health impacts.

Are there alternatives to (8alpha,9R)-10,11-Dihydrocinchonan-9-ol (CAS: 485-64-3) in synthesis?

Yes, there are several alternatives such as other cinchona alkaloids like quinine, or synthetic analogs like 6-methoxymethyldihydrocinchonan-9-ol. These alternatives can serve similar roles in chemical reactions, though they may have different reactivity and solubility profiles.

What is the market or research trend for (8alpha,9R)-10,11-Dihydrocinchonan-9-ol (CAS: 485-64-3)?

The market for (8alpha,9R)-10,11-Dihydrocinchonan-9-ol is currently stable with increasing interest in its use as a chiral auxiliary in organic synthesis. Research trends indicate growing focus on its potential applications in pharmaceuticals and agrochemicals, driven by its unique structural features and reactivity.

How should waste containing (8alpha,9R)-10,11-Dihydrocinchonan-9-ol (CAS: 485-64-3) be handled?

Waste containing this compound should be collected in appropriate containers and stored under controlled conditions to prevent degradation. It should be disposed of through professional waste disposal services that comply with local regulations. Environmental protection measures include minimizing spills and ensuring all waste is properly treated to prevent contamination of soil and water sources.