1,3-Dioxan-5-ol

Basic Information

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CAS Number

4740-78-7

Molecular Formula

C4H8O3

Molecular Weight

104.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

194°C

Flash Point

97 ºC

Refractive Index

1.45-1.452

SMILES

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OC1COCOC1

InChI

InChI=1S/C4H8O3/c5-4-1-6-3-7-2-4/h4-5H,1-3H2

InChIKey

VCKSNYNNVSOWEE-UHFFFAOYSA-N

LogP

-0.6484000000000001

Topological Polar Surface Area

38.69 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

48.9

Safety Information

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GHS Hazard Pictograms

H227

Hazard Statement

H227 Combustible liquid
Flammable liquids

Hazard Class

Class Comb liq Class Comb liq

Synonyms & References

English

1,3-Dioxan-5-ol
1,3-Formalglycerol
5-Hydroxy-1,3-dioxane
5-Hydroxy-m-dioxane
m-Dioxan-5-ol
Glycerol F0rmal
Glycerol formal
METHYLIDINOGLYCEROL, SERICOSOL N., GLICERINFORMAL0
Glycerol formal, alpha,alpha'
F6UP32GBII
VCKSNYNNVSOWEE-UHFFFAOYSA-N
5-m-dioxanol
META-DIOXAN-5-OL
KSC498E6N
BBL011466
STL146578
CHM0078800
SY039164
AX8054210

MDL Number

MFCD00014645

Customs Code

2942000000

FAQ

What is 1,3-Dioxan-5-ol (CAS: 4740-78-7)?

1,3-Dioxan-5-ol, also known as 5-hydroxy-1,3-dioxane, is a cyclic ether with the chemical formula C4H8O3. It is a colorless, flammable liquid with a mild odor. It is commonly used in the synthesis of pharmaceuticals, as a solvent in organic chemistry, and in the food industry as an aroma compound. It is a key intermediate in the production of other organic compounds.

What are the main uses of 1,3-Dioxan-5-ol (CAS: 4740-78-7)?

1,3-Dioxan-5-ol is widely used in the pharmaceutical industry for the synthesis of various drugs, including antibiotics, antivirals, and anti-inflammatory agents. It is also employed as a solvent in organic chemistry due to its low vapor pressure and good solubility for many organic compounds. In the food industry, it functions as an aroma compound, enhancing the flavor of certain foods and beverages.

Is 1,3-Dioxan-5-ol (CAS: 4740-78-7) safe?

1,3-Dioxan-5-ol is considered generally safe for industrial use, but it is important to handle it with care. It is mildly toxic by oral ingestion and exposure to high concentrations can irritate skin and eyes. Workers should wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. It is advisable to handle it in a well-ventilated area and avoid contact with skin and eyes. Storage and handling should adhere to local safety standards and guidelines.

How should 1,3-Dioxan-5-ol (CAS: 4740-78-7) be stored?

1,3-Dioxan-5-ol should be stored in a cool, dry place away from direct sunlight and heat sources. It is best kept in a tightly sealed container to prevent contamination and degradation. The storage temperature should ideally be below 25°C (77°F) to maintain its stability. Avoid storing it in high humidity areas as moisture can affect its quality. Ensure containers are well-labeled and kept away from incompatible substances such as acids and oxidizers.