Trifluoperazine dihydrochloride

Basic Information

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CAS Number

440-17-5

Molecular Formula

C21H26Cl2F3N3S

Molecular Weight

480.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

243 °C (dec.)

Boiling Point

506°C at 760 mmHg

Flash Point

9℃

Solubility

ethanol: soluble5mg/mL

SMILES

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CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F.Cl.Cl

InChI

InChI=1S/C21H24F3N3S.2ClH/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24;;/h2-3,5-8,15H,4,9-14H2,1H3;2*1H

InChIKey

BXDAOUXDMHXPDI-UHFFFAOYSA-N

LogP

5.789200000000005

pKa

pK1 3.9, pK2 8.1(at 25℃)

Topological Polar Surface Area

9.72 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

510

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Stability

Hygroscopic

Synonyms & References

English

Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-, dihydrochloride
Triftazin
NCGC00094474-03
10H-Phenothiazine, 10-(3-(4-methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)-, hydrochloride (1:2)
A826478
Trifluoperazine 2HCl
TRIFLUOPERAZINE HYDROCHLORIDE (EP MONOGRAPH)
TRIFLUOPERAZINE HYDROCHLORIDE [VANDF]
Prestwick_482
Tox21_110017_1
SB19410
DTXSID1045085
Trifluoroperazine dihydrochloride
EU-0101232
CCG-40290
Trifluperazine dihydrochloride
10H-phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, dihydrochloride
Tryptazine
D00799
Jatroneural
NCGC00094474-01
SR-01000003020
EN300-122645
Modalina
Trifluoroperazine hydrochloride
10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine dihydrochloride
NCGC00013226-01
10-(3-(4-methylpiperazin-1-yl)propyl)-2-(trifluoromethyl)-10H-phenothiazine dihydrochloride
Terfluzine
NSC-757369
10-(3-(4-Methyl-1-piperazinyl)propyl)-2-(trifluoromethyl)phenothiazine dihydrochloride

MDL Number

MFCD00012656

Customs Code

29343000

FAQ

What regulatory guidelines apply to Trifluoperazine dihydrochloride (CAS: 440-17-5)?

Trifluoperazine dihydrochloride (CAS: 440-17-5) is regulated under several guidelines including GHS classification, EU REACH regulations, FDA and EPA requirements. It is classified as an antipsychotic and is subject to strict control due to its psychoactive properties. Specific handling, storage, and waste disposal procedures must be followed to ensure compliance with regulatory standards.

Are there alternatives to Trifluoperazine dihydrochloride (CAS: 440-17-5) in synthesis?

For synthesis purposes, alternatives to Trifluoperazine dihydrochloride (CAS: 440-17-5) include other antipsychotic drugs such as haloperidol or clozapine. These alternatives can serve as effective substitutes in various synthesis pathways. It is important to evaluate the specific requirements of the synthesis to determine the most suitable alternative.

What is the market or research trend for Trifluoperazine dihydrochloride (CAS: 440-17-5)?

The market for Trifluoperazine dihydrochloride (CAS: 440-17-5) is primarily driven by its use in psychiatric treatments. Research trends are focusing on understanding its mechanism of action, potential side effects, and comparing it with newer antipsychotic drugs. Additionally, there is an increasing interest in its potential applications beyond traditional psychopharmacology, such as in neuroprotection and neurodegenerative disorders.

How should waste containing Trifluoperazine dihydrochloride (CAS: 440-17-5) be handled?

Waste containing Trifluoperazine dihydrochloride (CAS: 440-17-5) should be collected in appropriate, labeled containers and stored in a secure, well-ventilated area. Disposal should follow specific environmental regulations, typically involving incineration or professional waste disposal services. Proper handling and disposal are crucial to prevent environmental contamination and ensure worker safety.