5-Bromo-6-methyl-2-pyridinamine

Basic Information

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CAS Number

42753-71-9

Molecular Formula

C6H7BrN2

Molecular Weight

187.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

81.0 to 85.0 deg-C

Boiling Point

234.3℃ at 760 mmHg

Refractive Index

1.5500 (estimate)

SMILES

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CC1=C(C=CC(=N1)N)Br

InChI

InChI=1S/C6H7BrN2/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3,(H2,8,9)

InChIKey

SEOZHXRTVJPQPZ-UHFFFAOYSA-N

LogP

1.73472

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

97.1

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Hygroscopic

Synonyms & References

English

MFCD00068230
CS-W007550
FT-0601876
J-517135
EN300-91286
BCP22089
42753-71-9
2-amino-5-bromo-6-picoline
AM62345
AKOS000268954
6-Amino-3-bromo-2-methylpyridine, 97%
4JO
6-Amino-3-bromo-2-methylpyridine
6-Amino-3-bromo-2-picoline (6-Amino-3-bromo-2-methylpyridine)
5-Bromo-6-methylpyridin-2-amine
2-Pyridinamine, 5-bromo-6-methyl-
DU7SD24F59
5-bromo-6-methyl-pyridin-2-amine
6-amino-3-bromo-2-methyl-pyridine
AC-2958
F8881-6528
2-Amino-5-bromo-6-methylpyridine
5-Bromo-6-methyl-2-pyridinamine
3-bromo-2-methyl-6-aminopyridine
InChI=1/C6H7BrN2/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3,(H2,8,9)
DTXSID8068414
SY003423
SCHEMBL117968
SEOZHXRTVJPQPZ-UHFFFAOYSA-
6-Amino-3-bromo-2-picoline
Q27454754

MDL Number

MFCD00068230

Customs Code

29333999

FAQ

What are the physical and chemical properties of 5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9)?

5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9) is a crystalline solid with a molecular weight of approximately 184.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is commonly used in the synthesis of pharmaceuticals and functional materials.

How is 5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9) typically synthesized?

5-Bromo-6-methyl-2-pyridinamine can be synthesized through the bromination of 6-methyl-2-pyridinamine followed by amination. Commonly, this involves the use of bromine in the presence of a catalyst such as sodium hypobromite. The reaction is conducted under mild conditions, and the product is isolated through crystallization and purification techniques.

What industries use 5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9)?

5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9) is primarily used in the pharmaceutical industry for the development of drug intermediates. It also finds applications in the polymer industry for the synthesis of functional polymers, as a reagent in sensor technology, and in the semiconductor industry for the production of electronic materials.

What precautions should be taken when handling 5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9)?

When handling 5-Bromo-6-methyl-2-pyridinamine (CAS: 42753-71-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhaling fumes. In case of a spill, spill kits should be used, and the area should be cleaned immediately. Always refer to the safety data sheet (SDS) for detailed safety information and emergency procedures.