2-Chloro-1-(2,4-dichlorophenyl)ethanone

Basic Information

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CAS Number

4252-78-2

Molecular Formula

C8H5Cl3O

Molecular Weight

223.49 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

53.0 to 57.0 deg-C

Boiling Point

130-135 °C/4 mmHg

Water Solubility

60 mg/L (20 ºC)

Solubility

60 mg/L (20°C)

Refractive Index

1.5510 (estimate)

SMILES

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C1=CC(=C(C=C1Cl)Cl)C(=O)CCl

InChI

InChI=1S/C8H5Cl3O/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3H,4H2

InChIKey

VYWPPRLJNVHPEU-UHFFFAOYSA-N

LogP

3.414900000000001

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

172

Safety Information

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GHS Hazard Pictograms

H315

H317

H318

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 9 Class 9

Sensitiveness

Lachrymatory

Synonyms & References

English

.alpha.,2,4-Trichloroacetophenone
FT-0609107
EN300-17947
2,2', 4'-trichloroacetophenone
2,2',4'-Trichloroacetophenone, 97%
2-chloro-1-(2,4-dichlorophenyl)ethan-1-one
UNII-2E35P7HJI2
Q10844265
DTXCID506190
2,2`,4`-Trichloroacetophenone
Tox21_113246
CS-0008216
1-(2,4-dichlorophenyl)-2-chloroethan-1 -one
NCGC00091258-01
A825923
Acetophenone, 2,2',4'-trichloro-
NCGC00091258-04
STR01461
Tox21_113461_1
AC-10643
Z57127890
2-chloranyl-1-(2,4-dichlorophenyl)ethanone
Tox21_200671
2,2',4'-TRICHLORO PHENYL ETHANONE
1-(2,4-dichlorophenyl)-2-chloroethan-1-one
2-chloro-1-(2', 4'-dichlorophenyl) ethanon
2-chloro-1-(2,4-dichlorophenyl)-ethanone
4252-78-2
Ethanone, 2-chloro-1-(2,4-dichlorophenyl)-
CCRIS 633
.omega.-Chloro-2,4-dichloroacetophenone

MDL Number

MFCD00000934

Customs Code

29147090

FAQ

What is 2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2)?

2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2) is a chlorinated ketone with the chemical formula C8H6Cl4O. It is a white crystalline solid with low solubility in water but moderate solubility in organic solvents. The compound is known for its aromatic structure and is commonly used as an intermediate in organic synthesis, particularly in pharmaceutical and industrial applications.

What are the main uses of 2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2)?

2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2) is primarily used in pharmaceuticals for the synthesis of agrochemicals and drug compounds. It serves as a key intermediate in producing herbicides and insecticides, and is also utilized in industrial chemical manufacturing. Additionally, it finds applications in research for developing new organic materials and functional chemicals.

Is 2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2) safe?

2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2) is considered toxic and requires careful handling. It may cause skin and eye irritation, and prolonged exposure can lead to respiratory issues. Safety standards emphasize the use of protective equipment, such as gloves and goggles, and proper ventilation. It is classified as a hazardous chemical under OSHA and GHS guidelines, necessitating adherence to specific safety protocols during storage and use.

How should 2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2) be stored?

2-Chloro-1-(2,4-dichlorophenyl)ethanone (CAS: 4252-78-2) should be stored in a tightly sealed, light-resistant container in a cool, dry place with controlled temperature (below 25°C) and humidity (less than 60%). Avoid exposure to heat, moisture, and direct light to maintain stability. It is recommended to store in a well-ventilated area and keep away from incompatible substances.