2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol

Basic Information

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CAS Number

41175-50-2

Molecular Formula

C12H15NO

Molecular Weight

189.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

131.0 to 136.0 deg-C

Boiling Point

374.4℃ at 760 mmHg

Water Solubility

Soluble in water (partly), ethanol, chloroform, methanol, and acetone.

SMILES

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C1CC2=C3C(=C(C=C2)O)CCCN3C1

InChI

InChI=1S/C12H15NO/c14-11-6-5-9-3-1-7-13-8-2-4-10(11)12(9)13/h5-6,14H,1-4,7-8H2

InChIKey

FOFUWJNBAQJABO-UHFFFAOYSA-N

LogP

2.091

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

218

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

SR-01000391415-1
41175-50-2
2,3,6,7-Tetrahydro-1H,5H-benzo[ij]quinolizin-8-ol
8-hydroxy julolidine
Oprea1_302656
1H,5H-Benzo(ij)quinolizin-8-ol, 2,3,6,7-tetrahydro-
C12H15NO
1-azatricyclo[7.3.1.05,13]trideca-5,7,9(13)-trien-6-ol
UNII-SDF5635X33
A873123
F9995-0032
SDF5635X33
AKOS000266870
DS-16292
NS00030934
SCHEMBL57822
EN300-06125
FOFUWJNBAQJABO-UHFFFAOYSA-
MFCD00006918
BCP17314
2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol #
EINECS 255-247-9
1H,5H-Benzo[ij]quinolizin-8-ol, 2,3,6,7-tetrahydro-
8-Hydroxyjulolidine, 97%
AC-23080
CS-D0243
AMY10195
SY038919
Z56928944
1-azatricyclo[7.3.1.0,5,13]trideca-5(13),6,8-trien-6-ol
F51881

MDL Number

MFCD00006918

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol (CAS: 41175-50-2)?

2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol is a white crystalline solid with a molecular weight of approximately 276.31 g/mol. It is slightly soluble in water and has a basic pH. It is reactive towards acid and can undergo nucleophilic substitution reactions. The compound is stable under normal conditions but should be stored in a closed container to prevent moisture absorption.

How is 2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol (CAS: 41175-50-2) typically synthesized?

2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol is typically synthesized via the condensation reaction of 1,2-diaminoquinoline with 1,3-diketone. The reaction is conducted in the presence of a base such as sodium hydroxide, followed by hydrolysis under acidic conditions. The yield is generally around 70-80%, and the reaction is selective for the desired product.

What industries use 2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol (CAS: 41175-50-2)?

2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol is mainly used in the pharmaceutical industry for its potential as an intermediate in drug synthesis. It is also utilized in the polymer industry for the development of functional materials and in the sensor industry for its ability to detect specific analytes. Additionally, it has shown promise in the semiconductor industry as a dopant.

What precautions should be taken when handling 2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol (CAS: 41175-50-2)?

When handling 2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.