3-Amino-5-chloropicolinonitrile

Basic Information

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CAS Number

408538-29-4

Molecular Formula

C6H4ClN3

Molecular Weight

153.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=C(C=NC(=C1N)C#N)Cl

InChI

InChI=1S/C6H4ClN3/c7-4-1-5(9)6(2-8)10-3-4/h1,3H,9H2

InChIKey

MIPHUHMTGIOLGI-UHFFFAOYSA-N

Complexity

162

Synonyms & References

English

3-amino-5-chloro-2-Pyridinecarbonitrile
3-Amino-5-chloropicolinonitrile
3-amino-5-chloropyridine-2-carbonitrile
AB41049
F95033
MIPHUHMTGIOLGI-UHFFFAOYSA-N
408538-29-4
3-AMINO-5-CHLORO-2-CYANOPYRIDINE
2-Pyridinecarbonitrile, 3-amino-5-chloro-
3-amino -2-cyano-5-chloropyridine
3-AMINO-5-CHLOROPYRIDINE-2-CARBONITRILE
3-amino-2-cyano-5-chloropyridine
MFCD07375051
AKOS006285106
DB-122553
DTXSID30708845
AS-10346
SCHEMBL125638
CS-0370470
A857672

MDL Number

MFCD07375051

FAQ

What are the physical and chemical properties of 3-Amino-5-chloropicolinonitrile (CAS: 408538-29-4)?

3-Amino-5-chloropicolinonitrile is a white crystalline solid with a molecular weight of approximately 220.58 g/mol. It is soluble in water and organic solvents such as methanol and ethanol. This compound is moderately reactive, particularly with nucleophiles, and it is commonly used in organic synthesis due to its functional groups. It has a melting point around 195-200°C.

How is 3-Amino-5-chloropicolinonitrile (CAS: 408538-29-4) typically synthesized?

3-Amino-5-chloropicolinonitrile is typically synthesized via the reaction of 5-chloropicolinonitrile with an amine, such as aniline, in the presence of a base like potassium carbonate. The reaction proceeds via nucleophilic substitution, yielding a high yield of the target compound with good selectivity.

What industries use 3-Amino-5-chloropicolinonitrile (CAS: 408538-29-4)?

3-Amino-5-chloropicolinonitrile is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the development of new materials, including polymers and sensors, due to its functional groups. Additionally, it has potential applications in the semiconductor industry for certain chemical processes.

What precautions should be taken when handling 3-Amino-5-chloropicolinonitrile (CAS: 408538-29-4)?

When handling 3-Amino-5-chloropicolinonitrile, it is important to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and the area should be monitored for any leaks or spills. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.