Compound Q&A

How is 3-Amino-5-chloropicolinonitrile (CAS: 408538-29-4) typically synthesized?

Answer

3-Amino-5-chloropicolinonitrile
3-Amino-5-chloropicolinonitrile is typically synthesized via the reaction of 5-chloropicolinonitrile with an amine, such as aniline, in the presence of a base like potassium carbonate. The reaction proceeds via nucleophilic substitution, yielding a high yield of the target compound with good selectivity.

About

English Name 3-Amino-5-chloropicolinonitrile
Molecular Formula C6H4ClN3
Molecular Weight 153.57 g/mol
SMILES C1=C(C=NC(=C1N)C#N)Cl
InChIKey MIPHUHMTGIOLGI-UHFFFAOYSA-N
Last Updated: 2026-03-01 17:11

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